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Biology and Evolution of Microorganisms

The Biology and Evolution of Microorganisms Group, whose head is Dr. Rafael Cantón and which is made up of nine other principal investigators as well as numerous pre- and post-doctoral researchers, technicians and other healthcare personnel, has participated in the last 5 years in 17 national and international research projects and in 15 contracts with pharmaceutical companies or companies dedicated to in vitro diagnostics. During this period of time this work has resulted in more than 190 publications in national and international journals with a high impact index and more than 11 doctoral theses. Likewise, more than 400 communications have been presented at numerous national and international congresses. And all this always seeking the highest excellence in the fields of population biology, antibiotic resistance, respiratory infection, microbiota, metagenomics and HIV.

Search for publications

Only original articles, editorials, guidelines.

  • Serrano-Tomás MI, Contreras-Romero P, Parellada M, Chaves-Cordero J, Zamora J, Hengst M, Pozo P, del Campo R, Guzmán-Salas S.

    Recognition of the microbial metabolite p-cresol in autism spectrum disorder: systematic review and meta-analysis

    FRONTIERS IN MOLECULAR NEUROSCIENCE . 18: 1576388-1576388. Number of citations: 2

    [doi:10.3389/fnmol.2025.1576388]

  • Ramiro-Martínez P, de Quinto I, Lanza VF, Gama JA, Rodríguez-Beltrán J.

    Universal rules govern plasmid copy number.

    NATURE COMMUNICATIONS . 16(1): 6022-6022. Number of citations: 4

    [doi:10.1038/s41467-025-61202-5]

  • Reinosa R, Troyano-Hernáez P, Valadés-Alcaraz A, Holguín Á.

    EpiMolBio: A novel user-friendly bioinformatic program for genetic variability analysis

    Computational and Structural Biotechnology Journal . 27: 2968-2975.

    [doi:10.1016/j.csbj.2025.06.034]

  • Rodríguez-Goncer I, Ruiz-Arabi E, Herrera S, Sabé N, Los-Arcos I, Silva JT, Pérez-Nadales E, Machuca I, Álvarez R, Valerio M, Castón JJ, Aguilera V, Bodro M, Cano Á, Cantón R, Carmona P, Carratalà J, Cordero E, Cruzado JM, Fariñas MC, Fernández-Ruiz M, Fondevila C, Fortún J, García-Cosío MD, Gutiérrez-Dalmau A, Iturbe D, Justo I, Len O, López-Medrano F, López Oliva MO, Martín-Dávila P, Martínez-Martínez L, Mazuecos A, Mirabet S, Muñoz P, Oliver A, Pérez-Sáez MJ, Rodríguez-Gómez J, San-Juan R, Sánchez-Céspedes J, Solé A, Vidal Verdú E, Villa J, Torre-Cisneros J, Aguado JM.

    Management of multidrug-resistant gram-negative bacilli infections in adult solid organ transplant recipients: GESITRA-IC/SEIMC, CIBERINFEC, and SET recommendations update.

    TRANSPLANTATION REVIEWS . 39(3): 100937-100937. Number of citations: 2

    [doi:10.1016/j.trre.2025.100937]

  • Baquero F, Cantón R, Pérez-Cobas AE, Coque TM, Levin B, Rodríguez-Beltrán J.

    Antechodynamics and Antechokinetics: Dynamics and Kinetics of Antibiotic Resistance Biomolecules

    Biomolecules . 15(6): . Number of citations: 2

    [doi:10.3390/biom15060823]

  • Boattini M, Bianco G, Bastos P, Mavromanolaki VE, Maraki S, Spiliopoulou A, Kakouris V, Kalchev Y, Budimir A, Bedenic B, Rubic Z, Licker M, Musuroi C, Juhász E, Kristóf K, Pirs M, Velimirovic I, Berktold M, Liptáková A, Krajcikova A, Drevinek P, Gryndlerova A, Brzychczy-Wloch M, Olechowska-Jarzab A, Bielec F, Brauncajs M, Podsiadly E, Nurzynska G, Zalas-Wiecek P, Riesbeck K, Andersson HS, Tønjum T, Berild JC, Leegaard TM, Rasmussen AN, Schønning K, Glöckner S, Rödel J, Badr MT, Häcker GA, Stark D, Hamprecht A, Dudakova A, Jantsch J, Mancini S, Quiblier C, Jacot D, Greub G, Ferniani T, Ambretti S, Calvo M, Stefani S, Schade R, Yusuf E, Koeveringe SVK, Vandamme S, Verroken A, Rodriguez-Villalobos H, Duigou F, Corvec S, Floch P, Massip C, Chainier D, Barraud O, Louissaint MB, Mizrahi A, Ali S, Doyle M, Egan C, McNicholas S, Colomina-Rodriguez J, Torres I, Luengo RG, Escartín MNL, Perez MBV, Halperin AV, García SF, Cantón R, Seruca M, Mendes VS, Carvalho D, Cavallo R, Cristino JM, Costa C.

    Diagnostic and epidemiological landscape of anaerobic bacteria in Europe, 2020-2023 (ANAEuROBE)

    INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS . 65(6): 107478-107478. Number of citations: 3

    [doi:10.1016/j.ijantimicag.2025.107478]

  • Ortiz-Miravalles L, Prieto A, Kieffer N, Vergara E, Cantón R, San Millán Á, Baquero F, Hipólito A, Escudero JA.

    Effect of oxygen on antimicrobial resistance genes from a one health perspective.

    The Science of the total environment . 979: 179523-179523. Number of citations: 1

    [doi:10.1016/j.scitotenv.2025.179523]

  • Maruri-Aransolo A, Quintana E, Michelena-González M, Pastor-Vivero MD, Álvarez A, Girón R, Alarcón T, Luna-Paredes C, Máiz L, Vicente S, de Valbuena MR, Prados MC, Castillo-Corullón S, Selma MJ, Solé A, Cols-Roig M, Mondéjar-López P, Ruiz EP, Olveira C, Aguilera PC, Ruiz PB, Causapé CL, Figuerola J, Asensio O, Caballero-Pérez JD, Cantón R.

    Bronchopulmonary colonization patterns in Spanish people with cystic fibrosis: Results of a national multicentre study.

    Enfermedades Infecciosas Y Microbiologia Clinica (english Ed.) . 43(6): 309-316.

    [doi:10.1016/j.eimce.2024.08.008]

  • Gayoso-Cantero D, Corbacho-Loarte MD, Crespillo-Andújar C, Chamorro-Tojeiro S, Norman F, Perez-Molina JA, González-Sanz M, Martín O, Rubio JM, Gullón-Peña B, Del Campo Albendea L, López-Vélez R, Monge-Maillo B.

    Changes in Lipid Profile Secondary to Asymptomatic Malaria in Migrants from Sub-Saharan Africa: A Retrospective Analysis of a 2010-2022 Cohort

    Tropical Medicine and Infectious Disease . 10(5): . Number of citations: 2

    [doi:10.3390/tropicalmed10050134]

  • Pastor-Vivero MD, Costa I Colomer J, Martín de Vicente C, Vicente-Santamaria S, Garcia Romero R, González Jiménez D, Luna Paredes C.

    Advances in the treatment of cystic fibrosis: CFTR modulators.

    Anales De Pediatria . 102(5): 503857-503857.

    [doi:10.1016/j.anpede.2025.503857]

  • Rodriguez-Temporal D, Adrados D, Alastruey-Izquierdo A, Alkorta M, Candela A, Canut A, Castro C, Cilla CG, de Dios Caballero J, Ercibengoa M, Fernández M, Fradejas I, Fraile O, Goyanes MJ, Gutiérrez A, López JI, López C, López-Calleja AI, López-Medrano R, Muñoz P, Ortega AM, Oviaño M, Peman J, Rodríguez-Mayo M, Ruiz A, Tristancho A, Rodríguez-Sánchez B.

    Current Performance of MALDI-TOF Mass Spectrometry Databases for the Identification of Dermatophyte Species

    JOURNAL OF FUNGI . 11(5): . Number of citations: 3

    [doi:10.3390/jof11050356]

  • García Romero R, López Cárdenes C, Crehuá Gaudiza E, Álvarez Beltrán M, Murray Hurtado M, Tutau Gómez C, Loverdos Eseverri I, Torcuato Rubio E, García Volpe C, Salcedo Lobato E, Medina Martínez M, Martin Fernández C, Moreno Álvarez A, Reyes Domínguez A, González Jiménez D.

    Improvement of intestinal inflammation after treatment with CFTR modulators in cystic fibrosis patients.

    Anales De Pediatria . 102(5): 503836-503836.

    [doi:10.1016/j.anpede.2025.503836]

  • Crehuá-Gaudiza E, Vicente Santamaría S, Álvarez Beltrán M, Martín Fernández C, Tutau Gómez C, Loverdos Eseverri I, García Romero R, Torcuato Rubio E, Del Brío Castillo R, Garriga García M, Gascón Galindo C, Gutiérrez Martínez JR, Castro Millán AM, Sierra San Nicolás S, Ortiz Pérez P, García Volpe C, Salcedo Lobato E, De La Mano Hernández A, Fernández González SM, Reyes Domínguez A, Peña-Quintana L, González Jiménez D.

    Effect of cystic fibrosis modulator therapies on serum levels of fat-soluble vitamins.

    Jpgn Reports . 6(2): 146-152. Number of citations: 2

    [doi:10.1002/jpr3.70007]

  • Vicente-Santamaría S, Torres-Guerrero ME, García-González M, Tabares-González A, Gascón-Galindo C, López-Cárdenes CM, Blitz-Castro E, Morales-Tirado A, Mota Goitia MI, Gutiérrez Martínez JR, Tutau Gómez C, García Romero R, Salcedo Lobato E, Peña Quintana L, Reyes Domínguez A, Torcuato Rubio E, Ortiz Pérez P, Fernández-Lorenzo AE, Moreno Álvarez A, Boga AS, Romero Rey H, Álvarez Beltrán M, Masip Simo E, González Jiménez D.

    Assessment of cystic fibrosis related liver disease in a pediatric cohort

    GASTROENTEROLOGIA Y HEPATOLOGIA . 48(5): 502321-502321. Number of citations: 1

    [doi:10.1016/j.gastrohep.2024.502321]

  • De La Villa S, Escrihuela-Vidal F, Fernández-Hidalgo N, Escudero-Sánchez R, Cabezón I, Boix-Palop L, Díaz-Pollán B, Goikoetxea AJ, García-País MJ, Pérez-Rodríguez MT, Crespo Á, Buzón-Martín L, Sanz-Peláez O, Ramos-Merino L, Silvante F, Muñoz P.

    Ceftaroline for bloodstream infections caused by methicillin-resistant Staphylococcus aureus: a multicentre retrospective cohort study

    CLINICAL MICROBIOLOGY AND INFECTION . 31(5): 793-801. Number of citations: 6

    [doi:10.1016/j.cmi.2024.11.022]

  • de Córdoba-Ansón PF, Linares-Ambohades I, Baquero F, Coque TM, Pérez-Cobas AE.

    The Respiratory Tract Microbiome and Human Health

    Microbial Biotechnology . 18(5): . Number of citations: 3

    [doi:10.1111/1751-7915.70147]

  • Arredondo-Alonso S, Pöntinen AK, Gama JA, Gladstone RA, Harms K, Tonkin-Hill G, Thorpe HA, Simonsen GS, Samuelsen Ø, Johnsen PJ, Corander J.

    Plasmid-driven strategies for clone success in Escherichia coli

    NATURE COMMUNICATIONS . 16(1): 2921-2921. Number of citations: 10

    [doi:10.1038/s41467-025-57940-1]

  • Becerra-Aparicio F, Gómez-Zorrilla S, Hernández-García M, Xanthopoulou K, Gijón D, Siverio A, Berbel D, Cercenado E, Rivera A, De Malet A, Xercavins M, Ruiz De Gopegui E, Canoura-Fernández L, Martínez JA, Seral C, Del Pozo JL, Cotarelo M, Ponz R, Higgins PG, Durán-Jordà X, Cantón R, Oliver A, Horcajada JP, Ruiz-Garbajosa P.

    Whole Genome Sequencing Analysis of Klebsiella pneumoniae Isolates from Health Care-Associated Bacteremia of Urinary Origin in Spain: Findings from the Multicenter ITUBRAS-2 Cohort Study

    Open forum infectious diseases . 12(4): .

    [doi:10.1093/ofid/ofaf164]