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Biology and Evolution of Microorganisms

The Biology and Evolution of Microorganisms Group, whose head is Dr. Rafael Cantón and which is made up of nine other principal investigators as well as numerous pre- and post-doctoral researchers, technicians and other healthcare personnel, has participated in the last 5 years in 17 national and international research projects and in 15 contracts with pharmaceutical companies or companies dedicated to in vitro diagnostics. During this period of time this work has resulted in more than 190 publications in national and international journals with a high impact index and more than 11 doctoral theses. Likewise, more than 400 communications have been presented at numerous national and international congresses. And all this always seeking the highest excellence in the fields of population biology, antibiotic resistance, respiratory infection, microbiota, metagenomics and HIV.

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Only original articles, editorials, guidelines.

  • Halperin AV, Del Castillo Polo JA, Cortes-Cuevas JL, Cardenas Isasi MJ, Ampuero Morisaki M, Birch R, Sánchez Díaz AM, Cantón R.

    Impact of Automated Blood Culture Systems on the Management of Bloodstream Infections: Results from a Crossover Diagnostic Clinical Trial.

    Microbiology spectrum . : .

    [doi:10.1128/spectrum.01436-22]

  • Corbacho-Loarte MD, Crespillo-Andújar C, Chamorro-Tojeiro S, Norman F, Pérez-Molina JA, Martín O, Rubio JM, Gullón-Peña B, López-Vélez R, Monge-Maillo B.

    Screening of imported malaria infection in asymptomatic migrants from Sub-Saharan Africa: A retrospective analysis of a 2010-2019 cohort

    TRAVEL MEDICINE AND INFECTIOUS DISEASE . 49: 102411-102411. Number of citations: 3

    [doi:10.1016/j.tmaid.2022.102411]

  • Erdem F, Díez-Aguilar M, Oksuz L, Kayacan C, Abulaila A, Oncul O, Morosini MI, Cantón R, Aktas Z.

    Time kill-assays of antibiotic combinations for multidrug resistant clinical isolates of OXA-48 carbapenemase producing Klebsiella pneumoniae

    ACTA MICROBIOLOGICA ET IMMUNOLOGICA HUNGARICA . 69(3): 215-219. Number of citations: 1

    [doi:10.1556/030.2022.01785]

  • Kaci K, Del Caño R, Luna M, Milán-Rois P, Castellanos M, Abreu M, Cantón R, Galán JC, Somoza Á, Miranda R, González de Rivera G, García-Mendiola T, Lorenzo E.

    Paving the way to point of care (POC) devices for SARS-CoV-2 detection.

    Talanta . 247: 123542-123542. Number of citations: 4

    [doi:10.1016/j.talanta.2022.123542]

  • Marín-Miret J, González-Serrano F, Rosas T, Baixeras J, Latorre A, Pérez-Cobas AE, Moya A.

    Temporal variations shape the gut microbiome ecology of the moth Brithys crini

    ENVIRONMENTAL MICROBIOLOGY . 24(9): 3939-3953. Number of citations: 2

    [doi:10.1111/1462-2920.15952]

  • Díaz-García J, Gómez A, Alcalá L, Reigadas E, Sánchez-Carrillo C, Pérez-Ayala A, Gómez-García de la Pedrosa E, González-Romo F, Merino-Amador P, Cuétara MS, García-Esteban C, Quiles-Melero I, Zurita ND, Muñoz-Algarra M, Sánchez-Romero I, Durán-Valle MT, Sánchez-García A, Alcoceba E, Muñoz P, Escribano P, Guinea J.

    Evidence of Fluconazole-Resistant Candida parapsilosis Genotypes Spreading across Hospitals Located in Madrid, Spain and Harboring the Y132F ERG11p Substitution

    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY . 66(8): . Number of citations: 14

    [doi:10.1128/aac.00710-22]

  • Hernández-Aguado JJ, de La Fuente-Valero J, Ramírez Mena M, Ortega-Medina L, Vidart Aragón JA, Galán JC.

    Comparative pilot study about HPV test with partial genotyping in primary screening versus other strategies for cervical cancer population screening, CRYGEN 16/18 study.

    Enfermedades Infecciosas Y Microbiologia Clinica (english Ed.) . : .

    [doi:10.1016/j.eimce.2022.08.001]

  • Canton R, Doi Y, Simner PJ.

    Treatment of carbapenem-resistant Pseudomonas aeruginosa infections: a case for cefiderocol.

    EXPERT REVIEW OF ANTI-INFECTIVE THERAPY . 20(8): 1-18. Number of citations: 1

    [doi:10.1080/14787210.2022.2071701]

  • Hernández-Sampelayo T, Gómez-Pavón J, González Del Castillo J, Martín-Delgado MC, Martín Sánchez FJ, Martínez-Sellés M, Molero García JM, Moreno Guillén S, Rodríguez-Artalejo FJ, Ruiz-Galiana J, Cantón R, De Lucas Ramos P, García-Botella A, García-Lledó A, Calvo Rey P, Bouza E.

    COVID in Pediatric Age: an opinion paper.

    REVISTA ESPANOLA DE QUIMIOTERAPIA . 35(4): 333-343. Number of citations: 1

    [doi:10.37201/req/012.2022]

  • Hernández-García M, García-Castillo M, Bou G, Cercenado E, Delgado-Valverde M, Oliver A, Pitart C, Rodríguez-Lozano J, Tormo N, Melo-Cristino J, Pinto MF, Gonçalves E, Alves V, Vieira AR, Ramalheira E, Sancho L, Diogo J, Ferreira R, Cruz H, Chaves C, Duarte J, Pássaro L, Díaz-Regañón J, Cantón R.

    Imipenem-Relebactam Susceptibility in Enterobacterales Isolates Recovered from ICU Patients from Spain and Portugal (SUPERIOR and STEP Studies)

    Microbiology spectrum . : . Number of citations: 6

    [doi:10.1128/spectrum.02927-22]

  • Martins-Oliveira I, Pérez-Viso B, Silva-Dias A, Gomes R, Peixe L, Novais Â, Cantón R, Pina-Vaz C.

    Rapid Detection of Plasmid AmpC Beta-Lactamases by a Flow Cytometry Assay

    ANTIBIOTICS-BASEL . 11(8): .

    [doi:10.3390/antibiotics11081130]

  • Fluit AC, Bayjanov JR, Benaissa-Trouw BJ, Rogers MRC, Díez-Aguilar M, Cantón R, Tunney MM, Elborn JS, Ekkelenkamp MB.

    Whole-genome analysis of Haemophilus influenzae strains isolated from persons with cystic fibrosis.

    JOURNAL OF MEDICAL MICROBIOLOGY . 71(8): .

    [doi:10.1099/jmm.0.001570]

  • Trastoy R, Gonzalez-Alba JM, Soriano V, Rodriguez-Calviño JJ, de Mendoza C, Costa JJ, Cea M, Barbeito G, Corral O, Gómez-Gallego F, Pérez Del Molino ML, Carlos Galán J, Aguilera A.

    The unexpected high prevalence of HBV subgenotype D4 in patients with chronic hepatitis B in Galicia, a northwestern Spanish region, reflects strong links with Latin America

    JOURNAL OF CLINICAL VIROLOGY . 153: 105195-105195.

    [doi:10.1016/j.jcv.2022.105195]

  • Casado JL, Vizcarra P, Haemmerle J, Velasco H, Martín-Hondarza A, Rodríguez-Domínguez MJ, Velasco T, Martín S, Romero-Hernández B, Fernández-Escribano M, Vallejo A.

    Pre-existing T cell immunity determines the frequency and magnitude of cellular immune response to two doses of mRNA vaccine against SARS-CoV-2.

    Vaccine: X . 11: 100165-100165. Number of citations: 3

    [doi:10.1016/j.jvacx.2022.100165]

  • Romero-Hernández B, Martínez-García L, Rodríguez-Dominguez M, Martínez-Sanz J, Vélez-Díaz-Pallarés M, Pérez Mies B, Muriel A, Gea F, Pérez-Elías MJ, Galán JC.

    The Negative Impact of COVID-19 in HCV, HIV, and HPV Surveillance Programs During the Different Pandemic Waves.

    Frontiers in Public Health . 10: 880435-880435. Number of citations: 1

    [doi:10.3389/fpubh.2022.880435]

  • Troyano-Hernáez P, Reinosa R, Holguín A.

    Genetic Diversity and Low Therapeutic Impact of Variant-Specific Markers in HIV-1 Pol Proteins.

    FRONTIERS IN MICROBIOLOGY . 13: 866705-866705.

    [doi:10.3389/fmicb.2022.866705]

  • Pereira, Ana P., Antunes, Patricia, Willems, Rob, Corander, Jukka, Coque, Teresa M., Peixe, Luisa, Freitas, Ana R., Novais, Carla.

    Evolution of Chlorhexidine Susceptibility and of the EfrEF Operon among Enterococcus faecalis from Diverse Environments, Clones, and Time Spans

    Microbiology spectrum . 10(4): .

    [doi:10.1128/spectrum.01176-22]

  • Jiménez D, Martínez-Sanz J, Sainz T, Calvo C, Méndez-Echevarría A, Moreno E, Blázquez-Gamero D, Vizcarra P, Rodríguez M, Jenkins R, Sánchez-Conde M, Ron R, Norman F, Moreno S, Ferrer M, Serrano-Villar S.

    Differences in saliva ACE2 activity among infected and non-infected adult and pediatric population exposed to SARS-CoV-2.

    JOURNAL OF INFECTION . 85(1): 86-89.

    [doi:10.1016/j.jinf.2022.04.041]