Biology and Evolution of Microorganisms

The Biology and Evolution of Microorganisms Group, whose head is Dr. Rafael Cantón and which is made up of nine other principal investigators as well as numerous pre- and post-doctoral researchers, technicians and other healthcare personnel, has participated in the last 5 years in 17 national and international research projects and in 15 contracts with pharmaceutical companies or companies dedicated to in vitro diagnostics. During this period of time this work has resulted in more than 190 publications in national and international journals with a high impact index and more than 11 doctoral theses. Likewise, more than 400 communications have been presented at numerous national and international congresses. And all this always seeking the highest excellence in the fields of population biology, antibiotic resistance, respiratory infection, microbiota, metagenomics and HIV.

Search for publications

Only original articles, editorials, guidelines.

  • Candel FJ, Salavert M, Estella A, Ferrer M, Ferrer R, Gamazo JJ, García-Vidal C, Del Castillo JG, González-Ramallo VJ, Gordo F, Mirón-Rubio M, Pérez-Pallarés J, Pitart C, Del Pozo JL, Ramírez P, Rascado P, Reyes S, Ruiz-Garbajosa P, Suberviola B, Vidal P, Zaragoza R.

    Ten Issues to Update in Nosocomial or Hospital-Acquired Pneumonia: An Expert Review

    Journal Of Clinical Medicine . 12(20): . Number of citations: 13

    [doi:10.3390/jcm12206526]

  • Mbuagbaw L, Garcia C, Brenner B, Cecchini D, Chakroun M, Djiadeu P, Holguin A, Mor O, Parkin N, Santoro MM, Ávila-Ríos S, Fokam J, Phillips A, Shafer RW, Jordan MR.

    Checklist for studies of HIV drug resistance prevalence or incidence: rationale and recommended use

    The lancet. HIV . 10(10): 684-689. Number of citations: 10

    [doi:10.1016/S2352-3018(23)00173-X]

  • Martínez JL, Baquero F.

    What are the missing pieces needed to stop antibiotic resistance?

    Microbial Biotechnology . 16(10): 1900-1923. Number of citations: 8

    [doi:10.1111/1751-7915.14310]

  • Sanz-García F, Gil-Gil T, Laborda P, Blanco P, Ochoa-Sánchez LE, Baquero F, Martínez JL, Hernando-Amado S.

    Translating eco-evolutionary biology into therapy to tackle antibiotic resistance

    NATURE REVIEWS MICROBIOLOGY . 21(10): 671-685. Number of citations: 47

    [doi:10.1038/s41579-023-00902-5]

  • El Mammery A, Ramírez de Arellano E, Cañada-García JE, Cercenado E, Villar-Gómara L, Casquero-García V, García-Cobos S, Lepe JA, Ruiz de Gopegui Bordes E, Calvo-Montes J, Larrosa Escartín N, Cantón R, Pérez-Vázquez M, Aracil B, Oteo-Iglesias J.

    An increase in erythromycin resistance in methicillin-susceptible Staphylococcus aureus from blood correlates with the use of macrolide/lincosamide/streptogramin antibiotics. EARS-Net Spain (2004-2020)

    FRONTIERS IN MICROBIOLOGY . 14: 1220286-1220286. Number of citations: 9

    [doi:10.3389/fmicb.2023.1220286]

  • Perez-Cobas, Ana Elena, Ginevra, Christophe, Rusniok, Christophe, Jarraud, Sophie, Buchrieser, Carmen.

    The respiratory tract microbiome, the pathogen load, and clinical interventions define severity of bacterial pneumonia

    CELL REPORTS MEDICINE . 4(9): . Number of citations: 12

    [doi:10.1016/j.xcrm.2023.101167]

  • Albóniga OE, Moreno E, Martínez-Sanz J, Vizcarra P, Ron R, Díaz-Álvarez J, Rosas M, Sánchez-Conde M, Galán JC, Angulo S, Moreno S, Barbas C, Serrano-Villar S.

    Differential abundance of lipids and metabolites related to SARS-CoV-2 infection and susceptibility.

    SCIENTIFIC REPORTS . 13(1): 15124-15124. Number of citations: 7

    [doi:10.1038/s41598-023-40999-5]

  • Gracia-Ahufinger I, López-González L, Vasallo FJ, Galar A, Siller M, Pitart C, Bloise I, Torrecillas M, Gijón-Cordero D, Viñado B, Castillo-García J, Campo R, Mulet X, Madueño-Alonso A, Chamizo-López FJ, Arrastia-Erviti M, Galán-Sánchez F, Fernández-Quejo M, Rodríguez-Díaz JC, Gutiérrez-Zufiaurre MN, Rodríguez-Maresca MA, Ortega-Lafont MDP, Yagüe-Guirao G, Chaves-Blanco L, Colomina-Rodríguez J, Vidal-Acuña MR, Portillo ME, Franco-Álvarez de Luna F, Centelles-Serrano MJ, Azcona-Gutiérrez JM, Delgado-Iribarren García Campero A, Rey-Cao S, Muñoz P, Calvo-Montes J, Zboromyrska Y, Grandioso D, Càmara J, Cantón R, Larrosa-Escartín N, Díaz-Regañón J, Martínez-Martínez L.

    The CARBA-MAP study: national mapping of carbapenemases in Spain (2014-2018)

    FRONTIERS IN MICROBIOLOGY . 14: 1247804-1247804. Number of citations: 9

    [doi:10.3389/fmicb.2023.1247804]

  • Becerra-Aparicio F, Gómez-Zorrilla S, Hernández-García M, Gijón D, Siverio A, Berbel D, Sánchez-Carrillo C, Cercenado E, Rivera A, de Malet A, Xercavins M, Ruiz de Gopegui E, Canoura-Fernández L, Martínez JA, Seral C, Del Pozo JL, Cotarelo M, Díaz-Regañón J, Cantón R, Oliver A, Horcajada JP, Ruiz-Garbajosa P.

    Significant increase of CTX-M-15-ST131 and emergence of CTX-M-27-ST131 Escherichia coli high-risk clones causing healthcare-associated bacteraemia of urinary origin in Spain (ITUBRAS-2 project)

    The Journal of antimicrobial chemotherapy . 78(9): 2291-2296. Number of citations: 8

    [doi:10.1093/jac/dkad234]

  • de la Torre Tarazona, Erick, Jimenez, Daniel, Marcos-Mencia, Daniel, Mendieta-Baro, Alejandro, Rivera-Delgado, Alejandro, Romero-Hernandez, Beatriz, Muriel, Alfonso, Rodriguez-Dominguez, Mario, Serrano-Villar, Sergio, Moreno, Santiago.

    The Influence of Pre-Existing Immunity against Human Common Cold Coronaviruses on COVID-19 Susceptibility and Severity

    Microbiology Research . 14(3): 1364-1375.

    [doi:10.3390/microbiolres14030093]

  • Hernández-González PI, Barquín J, Ortega-Ferrete A, Patón V, Ponce-Alonso M, Romero-Hernández B, Ocaña J, Caminoa A, Conde-Moreno E, Galeano J, Campo RD, García-Pérez JC.

    Anastomotic leak in colorectal cancer surgery: Contribution of gut microbiota and prediction approaches.

    COLORECTAL DISEASE . 25: 2187-2197. Number of citations: 6

    [doi:10.1111/codi.16733]

  • Salmerón P, Buckley C, Arando M, Alcoceba E, Romero B, Clavo P, Whiley D, Serra-Pladevall J.

    Genome-based epidemiology and antimicrobial resistance of Neisseria gonorrhoeae in Spain: A prospective multicentre study.

    JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY . 37: 2575-2582. Number of citations: 1

    [doi:10.1111/jdv.19458]

  • Pérez-Cobas AE, Rodríguez-Beltrán J, Baquero F, Coque TM.

    Ecology of the respiratory tract microbiome.

    TRENDS IN MICROBIOLOGY . 31(9): 972-984. Number of citations: 24

    [doi:10.1016/j.tim.2023.04.006]

  • Maechler F, Schwab F, Hansen S, Behnke M, Bonten MJ, Canton R, Diaz Agero C, Fankhauser C, Harbarth S, Huttner BD, Kola A, Gastmeier P.

    Quantification of time delay between screening and subsequent initiation of contact isolation for carriers of extended-spectrum beta-lactamase (ESBL)-producing Enterobacterales: A post hoc subgroup analysis of the R-GNOSIS WP5 Trial.

    INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY . 44(9): 1-7. Number of citations: 2

    [doi:10.1017/ice.2022.285]

  • Ortiz-Cartagena C, Pablo-Marcos D, Fernández-García L, Blasco L, Pacios O, Bleriot I, Siller M, López M, Fernández J, Aracil B, Fraile-Ribot PA, García-Fernández S, Fernández-Cuenca F, Hernández-García M, Cantón R, Calvo-Montes J, Tomás M.

    CRISPR-Cas13a-Based Assay for Accurate Detection of OXA-48 and GES Carbapenemases.

    Microbiology spectrum . 11(4): . Number of citations: 12

    [doi:10.1128/spectrum.01329-23]

  • Baquero F.

    Imagining Kant's theory of scientific knowledge: philosophy and education in microbiology

    INTERNATIONAL MICROBIOLOGY . 26(3): 445-457. Number of citations: 6

    [doi:10.1007/s10123-022-00315-z]

  • Pérez-Molina JA, Crespillo-Andújar C, Trigo E, Chamorro S, Arsuaga M, Olavarrieta L, Navia B, Martín O, Monge-Maillo B, Norman FF, Lanza VF, Serrano-Villar S.

    Chagas disease is related to structural changes of the gut microbiota in adults with chronic infection (TRIPOBIOME Study).

    PLOS NEGLECTED TROPICAL DISEASES . 17(7): . Number of citations: 5

    [doi:10.1371/journal.pntd.0011490]

  • Serrano-Villar S, Tincati C, Raju SC, Sáenz JS, Moreno E, Bargiela R, Cabello-Ubeda A, Sendagorta E, Kurz A, Perez Molina JA, de Benito A, Hov JR, Fernandez-Lopez L, Muriel A, Del Campo R, Moreno S, Trøseid M, Seifert J, Ferrer M.

    Microbiome-derived cobalamin and succinyl-CoA as biomarkers for improved screening of anal cancer.

    NATURE MEDICINE . 29(7): 1738-1749. Number of citations: 15

    [doi:10.1038/s41591-023-02407-3]