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Biology and Evolution of Microorganisms

The Biology and Evolution of Microorganisms Group, whose head is Dr. Rafael Cantón and which is made up of nine other principal investigators as well as numerous pre- and post-doctoral researchers, technicians and other healthcare personnel, has participated in the last 5 years in 17 national and international research projects and in 15 contracts with pharmaceutical companies or companies dedicated to in vitro diagnostics. During this period of time this work has resulted in more than 190 publications in national and international journals with a high impact index and more than 11 doctoral theses. Likewise, more than 400 communications have been presented at numerous national and international congresses. And all this always seeking the highest excellence in the fields of population biology, antibiotic resistance, respiratory infection, microbiota, metagenomics and HIV.

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Only original articles, editorials, guidelines.

  • Muñoz-Cazalla A, de Quinto I, Álvaro-Llorente L, Rodríguez-Beltrán J, Herencias C.

    The role of bacterial metabolism in human gut colonization.

    INTERNATIONAL MICROBIOLOGY . : . Number of citations: 2

    [doi:10.1007/s10123-024-00550-6]

  • Pina-Vaz C, Silva-Dias A, Martins-Oliveira I, Gomes R, Perez-Viso B, Cruz S, Rodrigues AG, Sarmento A, Cantón R.

    A multisite validation of a two hours antibiotic susceptibility flow cytometry assay directly from positive blood cultures.

    BMC MICROBIOLOGY . 24(1): 187-187. Number of citations: 14

    [doi:10.1186/s12866-024-03341-1]

  • Fernández-Ruiz M, Gioia F, Bodro M, Gutiérrez Martín I, Sabé N, Rodriguez-Álvarez R, Corbella L, López-Viñau T, Valerio M, Illaro A, Salto-Alejandre S, Cordero E, Arnaiz de Las Revillas F, Fariñas MC, Muñoz P, Vidal E, Carratalà J, Goikoetxea J, Ramos-Martínez A, Moreno A, Martín-Dávila P, Fortún J, Aguado JM.

    Isavuconazole Versus Voriconazole as the First-line Therapy for Solid Organ Transplant Recipients With Invasive Aspergillosis: Comparative Analysis of 2 Multicenter Cohort Studies.

    TRANSPLANTATION . 108(11): 2260-2269. Number of citations: 7

    [doi:10.1097/TP.0000000000005082]

  • Aracil-Gisbert S, Fernández-de-Bobadilla MD, Guerra-Pinto N, Serrano-Calleja S, Pérez-Cobas AE, Soriano C, de Pablo R, Lanza VF, Pérez-Viso B, Reuters S, Hasman H, Cantón R, Baquero F, Coque TM.

    The ICU environment contributes to the endemicity of the "Serratia marcescens complex" in the hospital setting.

    mBio . 15(5): . Number of citations: 37

    [doi:10.1128/mbio.03054-23]

  • Salamanca-Rivera E, Palacios-Baena ZR, Cañada JE, Moure Z, Pérez-Vázquez M, Calvo-Montes J, Martínez-Martínez L, Cantón R, Ruiz Carrascoso G, Pitart C, Navarro F, Bou G, Mulet X, González-López JJ, Sivianes F, Delgado-Valverde M, Pascual Á, Oteo-Iglesias J, Rodríguez-Baño J.

    Epidemiological and clinical characterization of community, healthcare-associated and nosocomial colonization and infection due to carbapenemase-producing Klebsiella pneumoniae and Escherichia coli in Spain.

    INFECTION . 52(6): 2231-2240. Number of citations: 8

    [doi:10.1007/s15010-024-02267-0]

  • Asensio-Grau A, Ferriz-Jordán M, Hervás D, Heredia A, García-Hernández J, Garriga M, Masip E, Carmen Collado M, Andrés A, Ribes-Koninckx C, Calvo-Lerma J.

    Faecal lipid profile as a new marker of fat maldigestion, malabsorption and microbiota.

    PEDIATRIC RESEARCH . : . Number of citations: 3

    [doi:10.1038/s41390-024-03209-0]

  • Liljegren MM, Gama JA, Johnsen PJ, Harms K.

    The recombination initiation functions DprA and RecFOR suppress microindel mutations in Acinetobacter baylyi ADP1.

    MOLECULAR MICROBIOLOGY . 122(1): 1-10. Number of citations: 1

    [doi:10.1111/mmi.15277]

  • Pujol-Muncunill G, Navas-López VM, Ledder O, Cohen S, Lekar M, Turner D, Kolho KL, Levine A, Croft NM, Bronsky J, Shouval DS, Assa A, Harris R, Kiparissi F, Aloi M, Afzal NA, Tzivinikos C, Barrio J, Norden C, Vega MJB, Buderus S, de Valderrama AF, de Ridder L, García-Romero R, Medina E, Sánchez C, Velasco M, Vicente S, Wilson DC, Naik S, Hradsky O, Cococcioni L, Martin-de-Carpi J.

    STEP-CD study: ustekinumab use in paediatric Crohn's disease-a multicentre retrospective study from paediatric IBD Porto group of ESPGHAN.

    EUROPEAN JOURNAL OF PEDIATRICS . 183(8): 3253-3262. Number of citations: 13

    [doi:10.1007/s00431-024-05588-2]

  • Maruri-Aransolo A, de Dios Caballero J, Michelena M, Medina-Pascual MJ, Carrasco G, Asensio O, Cols M, Cantón R.

    Evaluation of CHROMagar™ B. cepacia agar for the detection of Burkholderia cepacia complex species from sputum samples of patients with cystic fibrosis.

    EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES . 43(7): 1349-1353. Number of citations: 2

    [doi:10.1007/s10096-024-04845-4]

  • Boattini M, Bianco G, Llorente LI, Acero LA, Nunes D, Seruca M, Mendes VS, Almeida A, Bastos P, Rodríguez-Villodres Á, Gascón AG, Halperin AV, Cantón R, Escartín MNL, González-López JJ, Floch P, Massip C, Chainier D, Barraud O, Dortet L, Cuzon G, Zancanaro C, Mizrahi A, Schade R, Rasmussen AN, Schønning K, Hamprecht A, Schaffarczyk L, Glöckner S, Rödel J, Kristóf K, Balonyi Á, Mancini S, Quiblier C, Fasciana T, Giammanco A, Paglietti B, Rubino S, Budimir A, Bedenic B, Rubic Z, Marinovic J, Gartzonika K, Christaki E, Mavromanolaki VE, Maraki S, Yalçin TY, Azap ÖK, Licker M, Musuroi C, Talapan D, Ovidiu VC, Comini S, Zalas-Wiecek P, Michalska A, Cavallo R, Cristino JM, Costa C.

    Enterobacterales carrying chromosomal AmpC ß-lactamases in Europe (EuESCPM): epidemiology and antimicrobial resistance burden from a cohort of 27 hospitals, 2020-2022.

    International Journal of Antimicrobial Agents . 63(5): 107115-107115. Number of citations: 28

    [doi:10.1016/j.ijantimicag.2024.107115]

  • Taylor-Salmon E, Hill V, Paul LM, Koch RT, Breban MI, Chaguza C, Sodeinde A, Warren JL, Bunch S, Cano N, Cone M, Eysoldt S, Garcia A, Gilles N, Hagy A, Heberlein L, Jaber R, Kassens E, Colarusso P, Davis A, Baudin S, Rico E, Mejía-Echeverri Á, Scott B, Stanek D, Zimler R, Muñoz-Jordán JL, Santiago GA, Adams LE, Paz-Bailey G, Spillane M, Katebi V, Paulino-Ramírez R, Mueses S, Peguero A, Sánchez N, Norman FF, Galán JC, Huits R, Hamer DH, Vogels CBF, Morrison A, Michael SF, Grubaugh ND.

    Travel surveillance uncovers dengue virus dynamics and introductions in the Caribbean.

    Nature Communications . 15(1): 3508-3508. Number of citations: 40

    [doi:10.1038/s41467-024-47774-8]

  • Silva V, Silva A, Barbero R, Romero M, Del Campo R, Caniça M, Cordeiro R, Igrejas G, Poeta P.

    Resistome, Virulome, and Clonal Variation in Methicillin-Resistant Staphylococcus aureus (MRSA) in Healthy Swine Populations: A Cross-Sectional Study.

    Genes . 15(5): . Number of citations: 5

    [doi:10.3390/genes15050532]

  • Monzón S, Varona S, Negredo A, Vidal-Freire S, Patiño-Galindo JA, Ferressini-Gerpe N, Zaballos A, Orviz E, Ayerdi O, Muñoz-Gómez A, Delgado-Iribarren A, Estrada V, García C, Molero F, Sánchez-Mora P, Torres M, Vázquez A, Galán JC, Torres I, Causse Del Río M, Merino-Diaz L, López M, Galar A, Cardeñoso L, Gutiérrez A, Loras C, Escribano I, Alvarez-Argüelles ME, Del Río L, Simón M, Meléndez MA, Camacho J, Herrero L, Jiménez P, Navarro-Rico ML, Jado I, Giannetti E, Kuhn JH, Sanchez-Lockhart M, Di Paola N, Kugelman JR, Guerra S, García-Sastre A, Cuesta I, Sánchez-Seco MP, Palacios G.

    Monkeypox virus genomic accordion strategies.

    Nature Communications . 15(1): 3059-3059. Number of citations: 49

    [doi:10.1038/s41467-024-46949-7]

  • Levin BR, Berryhill BA, Gil-Gil T, Manuel JA, Smith AP, Choby JE, Andersson DI, Weiss DS, Baquero F.

    Theoretical considerations and empirical predictions of the pharmaco- and population dynamics of heteroresistance.

    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA . 121(16): . Number of citations: 9

    [doi:10.1073/pnas.2318600121]

  • Castillo-Polo JA, Hernández-García M, Maruri-Aransolo A, de la Vega C, Ruiz-Garbajosa P, Cantón R.

    Evolution of ceftazidime-avibactam and cefiderocol resistance in ST131-H30R1-Escherichia coli isolates with KPC-3 mutants and application of FTIR biotyping.

    Microbiology Spectrum . 12(4): . Number of citations: 5

    [doi:10.1128/spectrum.02776-23]

  • Ruiz-Galiana, Julian, Canton, Rafael, De Lucas Ramos, Pilar, Garcia-Botella, Alejandra, Garcia-Lledo, Alberto, Hernandez-Sampelayo, Teresa, Gomez-Pavon, Javier, Gonzalez del Castillo, Juan, Martin-Delgado, Mari Cruz, Martin Sanchez, Francisco Javier, Martinez-Selles, Manuel, Molero Garcia, Jose Maria, Moreno Guillen, Santiago, Rodriguez-Artalejo, Fernando, Rodriguez Fernandez, Rosa, Kestler, Marta, Bouza, Emilio.

    Respiratory syncytial virus: A new era

    Revista Espanola de Quimioterapia . 37(2): 134-148. Number of citations: 26

    [doi:10.37201/req/147.2023]

  • Ismail AS, Berryhill BA, Gil-Gil T, Manuel JA, Smith AP, Baquero F, Levin BR.

    The Tradeoffs Between Persistence and Mutation Rates at Sub-Inhibitory Antibiotic Concentrations in Staphylococcus aureus.

    Biorxiv : The Preprint Server For Biology . : .

    [doi:10.1101/2024.04.01.587561]

  • Bosch-Nicolau P, Fernández ML, Sulleiro E, Villar JC, Perez-Molina JA, Correa-Oliveira R, Sosa-Estani S, Sánchez-Montalvá A, Del Carmen Bangher M, Moreira OC, Salvador F, Mota Ferreira A, Eloi-Santos SM, Serre-Delcor N, Ramírez JC, Silgado A, Oliveira I, Martín O, Aznar ML, Ribeiro ALP, Almeida PEC, Chamorro-Tojeiro S, Espinosa-Pereiro J, de Paula AMB, Váquiro-Herrera E, Tur C, Molina I.

    Efficacy of three benznidazole dosing strategies for adults living with chronic Chagas disease (MULTIBENZ): an international, randomised, double-blind, phase 2b trial.

    LANCET INFECTIOUS DISEASES . 24(4): 386-394. Number of citations: 42

    [doi:10.1016/S1473-3099(23)00629-1]