1. Home
  2. Research
  3. Research Groups
  4. Biology and Evolution of Microorganisms

Biology and Evolution of Microorganisms

The Biology and Evolution of Microorganisms Group, whose head is Dr. Rafael Cantón and which is made up of nine other principal investigators as well as numerous pre- and post-doctoral researchers, technicians and other healthcare personnel, has participated in the last 5 years in 17 national and international research projects and in 15 contracts with pharmaceutical companies or companies dedicated to in vitro diagnostics. During this period of time this work has resulted in more than 190 publications in national and international journals with a high impact index and more than 11 doctoral theses. Likewise, more than 400 communications have been presented at numerous national and international congresses. And all this always seeking the highest excellence in the fields of population biology, antibiotic resistance, respiratory infection, microbiota, metagenomics and HIV.

Search for publications

Only original articles, editorials, guidelines.

  • Cañada-García JE, Moure Z, Sola-Campoy PJ, Delgado-Valverde M, Cano ME, Gijón D, González M, Gracia-Ahufinger I, Larrosa N, Mulet X, Pitart C, Rivera A, Bou G, Calvo J, Cantón R, González-López JJ, Martínez-Martínez L, Navarro F, Oliver A, Palacios-Baena ZR, Pascual Á, Ruiz-Carrascoso G, Vila J, Aracil B, Pérez-Vázquez M, Oteo-Iglesias J.

    CARB-ES-19 Multicenter Study of Carbapenemase-Producing Klebsiella pneumoniae and Escherichia coli From All Spanish Provinces Reveals Interregional Spread of High-Risk Clones Such as ST307/OXA-48 and ST512/KPC-3

    FRONTIERS IN MICROBIOLOGY . 13: 918362-918362. Number of citations: 10

    [doi:10.3389/fmicb.2022.918362]

  • Fuchs F, Becerra-Aparicio F, Xanthopoulou K, Seifert H, Higgins PG.

    In vitro activity of nitroxoline against carbapenem-resistant Acinetobacter baumannii isolated from the urinary tract.

    JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY . 77(7): 1912-1915. Number of citations: 3

    [doi:10.1093/jac/dkac123]

  • Saralegui C, Herencias C, Halperin AV, de Dios-Caballero J, Pérez-Viso B, Salgado S, Lanza VF, Cantón R, Baquero F, Prieto MA, del Campo R.

    Strain-specific predation of Bdellovibrio bacteriovorus on Pseudomonas aeruginosa with a higher range for cystic fibrosis than for bacteremia isolates.

    SCIENTIFIC REPORTS . 12(1): 10523-10523. Number of citations: 3

    [doi:10.1038/s41598-022-14378-5]

  • Muñoz-Chimeno M, Bartúren S, García-Lugo MA, Morago L, Rodríguez Á, Galán JC, Pérez-Rivilla A, Rodríguez M, Millán R, Del Álamo M, Alonso R, Molina L, Aguinaga A, Avellón A.

    Hepatitis E virus genotype 3 microbiological surveillance by the Spanish Reference Laboratory: geographic distribution and phylogenetic analysis of subtypes from 2009 to 2019

    Eurosurveillance . 27(23): . Number of citations: 12

    [doi:10.2807/1560-7917.ES.2022.27.23.2100542]

  • Troyano-Hernáez P, Reinosa R, Holguín Á.

    Evolution of SARS-CoV-2 in Spain during the First Two Years of the Pandemic: Circulating Variants, Amino Acid Conservation, and Genetic Variability in Structural, Non-Structural, and Accessory Proteins.

    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES . 23(12): . Number of citations: 6

    [doi:10.3390/ijms23126394]

  • Feito, Javier, Araujo, Carlos, Gomez-Sala, Beatriz, Contente, Diogo, Campanero, Cristina, Arbulu, Sara, Saralegui, Claudia, Pena, Nuria, Munoz-Atienza, Estefania, Borrero, Juan, del Campo, Rosa, Hernandaz, Pablo E., Cintas, Luis M..

    Antimicrobial activity, molecular typing and in vitro safety assessment of Lactococcus garvieae isolates from healthy cultured rainbow trout (Oncorhynchus mykiss, Walbaum) and rearing environment

    LWT-FOOD SCIENCE AND TECHNOLOGY . 162: . Number of citations: 1

    [doi:10.1016/j.lwt.2022.113496]

  • Casado JL, Haemmerle J, Vizcarra P, Ramirez-Alonso G, Salazar-Tosco A, Romero-Hernandez B, Blasco M, Rodriguez-Dominguez M, Mirabella IG, Vallejo A, Fernandez-Escribano M.

    Risk of SARS-CoV-2 Reinfections in a Prospective Inception Cohort Study: Impact of COVID-19 Vaccination

    Journal Of Clinical Medicine . 11(12): . Number of citations: 2

    [doi:10.3390/jcm11123352]

  • Rodríguez Díaz C, Lafuente-Gómez N, Coutinho C, Pardo D, Alarcón-Iniesta H, López-Valls M, Coloma R, Milán-Rois P, Domenech M, Abreu M, Cantón R, Galán JC, Bocanegra R, Campos LA, Miranda R, Castellanos M, Somoza Á.

    Development of colorimetric sensors based on gold nanoparticles for SARS-CoV-2 RdRp, E and S genes detection.

    Talanta . 243: 123393-123393. Number of citations: 6

    [doi:10.1016/j.talanta.2022.123393]

  • Alshammari, N, Alazmi, M, Alanazi, NA, Sulieman, AME, Veettil, VN, Ponce-Alonso, M.

    A Comparative Study on the Microbial Communities of Rhynchophorus ferrugineus (Red Palm Weevil)-Infected and Healthy Palm Trees

    ARABIAN JOURNAL FOR SCIENCE AND ENGINEERING . 47(6): 6735-6746.

    [doi:10.1007/s13369-021-05979-9]

  • Valadés-Alcaraz A, Reinosa R, Holguín Á.

    HIV Transmembrane Glycoprotein Conserved Domains and Genetic Markers Across HIV-1 and HIV-2 Variants.

    FRONTIERS IN MICROBIOLOGY . 13: 855232-855232. Number of citations: 1

    [doi:10.3389/fmicb.2022.855232]

  • Rodríguez-Galet A, Rubio-Garrido M, Valadés-Alcaraz A, Rodríguez-Domínguez M, Galán JC, Ndarabu A, Reina G, Holguín A.

    Immune surveillance for six vaccinable pathogens using paired plasma and dried blood spots in HIV infected and uninfected children in Kinshasa.

    SCIENTIFIC REPORTS . 12(1): 7920-7920.

    [doi:10.1038/s41598-022-12052-4]

  • Fluit AC, Bayjanov JR, Aguilar MD, Cantón R, Elborn S, Tunney MM, Scharringa J, Benaissa-Trouw BJ, Ekkelenkamp MB.

    Taxonomic position, antibiotic resistance and virulence factor production by Stenotrophomonas isolates from patients with cystic fibrosis and other chronic respiratory infections.

    BMC MICROBIOLOGY . 22(1): 129-129. Number of citations: 1

    [doi:10.1186/s12866-022-02466-5]

  • López-Valls M, Escalona-Noguero C, Rodríguez-Díaz C, Pardo D, Castellanos M, Milán-Rois P, Martínez-Garay C, Coloma R, Abreu M, Cantón R, Galán JC, Miranda R, Somoza Á, Sot B.

    CASCADE: Naked eye-detection of SARS-CoV-2 using Cas13a and gold nanoparticles.

    ANALYTICA CHIMICA ACTA . 1205: 339749-339749. Number of citations: 8

    [doi:10.1016/j.aca.2022.339749]

  • Cortés A, Casado JL, Longo F, Serrano JJ, Saavedra C, Velasco H, Martin A, Chamorro J, Rosero D, Fernández M, Gion M, Martínez Jáñez N, Soria Rivas A, Alonso Gordoa T, Martínez Delfrade Í, Lage Y, López Miranda E, Olmedo ME, Reguera Puertas P, Gajate P, Molina Cerrillo J, Guerra Alia E, Fuentes Mateos R, Romero B, Rodríguez-Domínguez MJ, Vallejo A, Carrato A.

    Limited T cell response to SARS-CoV-2 mRNA vaccine among patients with cancer receiving different cancer treatments

    EUROPEAN JOURNAL OF CANCER . 166: 229-239. Number of citations: 12

    [doi:10.1016/j.ejca.2022.02.017]

  • Abichabki N, Zacharias LV, Moreira NC, Bellissimo-Rodrigues F, Moreira FL, Benzi JRL, Ogasawara TMC, Ferreira JC, Ribeiro CM, Pavan FR, Pereira LRL, Brancini GTP, Braga GÚL, Zuardi AW, Hallak JEC, Crippa JAS, Lanchote VL, Cantón R, Darini ALC, Andrade LN.

    Potential cannabidiol (CBD) repurposing as antibacterial and promising therapy of CBD plus polymyxin B (PB) against PB-resistant gram-negative bacilli

    SCIENTIFIC REPORTS . 12(1): 6454-6454. Number of citations: 11

    [doi:10.1038/s41598-022-10393-8]

  • Troyano-Hernáez P, Reinosa R, Holguín Á.

    HIV Capsid Protein Genetic Diversity Across HIV-1 Variants and Impact on New Capsid-Inhibitor Lenacapavir.

    FRONTIERS IN MICROBIOLOGY . 13: 854974-854974. Number of citations: 4

    [doi:10.3389/fmicb.2022.854974]

  • Do TT, Rodríguez-Beltran J, Cebrián-Sastre E, Rodríguez-Rojas A, Castañeda-García A, Blázquez J.

    Inactivation of a New Potassium Channel Increases Rifampicin Resistance and Induces Collateral Sensitivity to Hydrophilic Antibiotics in Mycobacterium smegmatis.

    ANTIBIOTICS-BASEL . 11(4): .

    [doi:10.3390/antibiotics11040509]

  • de Dios Caballero J, Cantón R, Ponce-Alonso M, García-Clemente MM, Gómez G de la Pedrosa E, López-Campos JL, Máiz L, Del Campo R, Martínez-García MÁ.

    The Human Mycobiome in Chronic Respiratory Diseases: Current Situation and Future Perspectives

    Microorganisms . 10(4): . Number of citations: 7

    [doi:10.3390/microorganisms10040810]