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Biology and Evolution of Microorganisms

The Biology and Evolution of Microorganisms Group, whose head is Dr. Rafael Cantón and which is made up of nine other principal investigators as well as numerous pre- and post-doctoral researchers, technicians and other healthcare personnel, has participated in the last 5 years in 17 national and international research projects and in 15 contracts with pharmaceutical companies or companies dedicated to in vitro diagnostics. During this period of time this work has resulted in more than 190 publications in national and international journals with a high impact index and more than 11 doctoral theses. Likewise, more than 400 communications have been presented at numerous national and international congresses. And all this always seeking the highest excellence in the fields of population biology, antibiotic resistance, respiratory infection, microbiota, metagenomics and HIV.

Search for publications

Only original articles, editorials, guidelines.

  • Gioia, F, Filigheddu, M T, Corbella, L, Fernandez-Ruiz, M, Lopez-Medrano, F, Perez-Ayala, A, Aguado, J M, Fariñas C, Arnaiz, F, Calvo, J, Cifrian, J M, Gonzalez-Rico, C, Vidal, E, Torre-Cisneros, J, Ras, M, Perez, S, Sabe, N, Lopez-Soria, L, Rodriguez-Alvarez, R, Montejo, J M, Valerio, M, Machado, M, Munoz, P, Linares, L, Bodro, M, Moreno, A, Fernandez-Cruz, A, Canton, R, Moreno, S, Martin-Davila, P, Fortun, J.

    Invasive aspergillosis in solid organ transplantation: Diagnostic challenges and differences in outcome in a Spanish national cohort (Diaspersot study)

    Mycoses . 64(11): 1334-1345. Number of citations: 1

    [doi:10.1111/myc.13298]

  • Hernández-García M, Díaz-Agero C, Pérez-Viso B, Sánchez AM, López-Fresneña N, Morosini MI, Ruiz-Garbajosa P, Cantón R.

    Implementation of contact isolation strategy for the containment of extended-spectrum beta-lactamase carriers in a University Hospital positively affects the epidemiology of carbapenemase-producing Enterobacterales

    ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA . 39(9): 429-435.

    [doi:10.1016/j.eimc.2020.05.013]

  • Bello, Salvador, Vengoechea, Jose J, Ponce-Alonso, Manuel, Figueredo, Ana L, Minchole, Elisa, Rezusta, Antonio, Gambo, Paula, Pastor, Juan Manuel, Javier Galeano, Del Campo, Rosa.

    Core Microbiota in Central Lung Cancer With Streptococcal Enrichment as a Possible Diagnostic Marker

    ARCHIVOS DE BRONCONEUMOLOGIA . 57(11): 681-689. Number of citations: 5

    [doi:10.1016/j.arbres.2020.05.034]

  • Baquero F, Martínez JL, Novais Â, Rodríguez-Beltrán J, Martínez-García L, Coque TM, Galán JC.

    Allogenous Selection of Mutational Collateral Resistance: Old Drugs Select for New Resistance Within Antibiotic Families

    FRONTIERS IN MICROBIOLOGY . 12: 757833-757833. Number of citations: 4

    [doi:10.3389/fmicb.2021.757833]

  • Gill CM, Aktaþ E, Alfouzan W, Bourassa L, Brink A, Burnham CA, Canton R, Carmeli Y, Falcone M, Kiffer C, Marchese A, Martinez O, Pournaras S, Seifert H, Thabit AK, Villegas MV, Westblade LF, Nicolau DP.

    Elevated MICs of Susceptible Anti-Pseudomonal Cephalosporins in Non-Carbapenemase-Producing, Carbapenem-Resistant Pseudomonas aeruginosa: Implications for Dose Optimization.

    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY . 65(11): . Number of citations: 4

    [doi:10.1128/AAC.01204-21]

  • Ferrer-Gómez A, Pian-Arias H, Carretero-Barrio I, Navarro-Cantero A, Pestaña D, de Pablo R, Zamorano JL, Galán JC, Pérez-Mies B, Ruz-Caracuel I, Palacios J.

    Late Cardiac Pathology in Severe Covid-19. A Postmortem Series of 30 Patients

    Frontiers in Cardiovascular Medicine . 8: 748396-748396. Number of citations: 5

    [doi:10.3389/fcvm.2021.748396]

  • López MG, Chiner-Oms Á, García de Viedma D, Ruiz-Rodriguez P, Bracho MA, Cancino-Muñoz I, D'Auria G, de Marco G, García-González N, Goig GA, Gómez-Navarro I, Jiménez-Serrano S, Martinez-Priego L, Ruiz-Hueso P, Ruiz-Roldán L, Torres-Puente M, Alberola J, Albert E, Aranzamendi Zaldumbide M, Bea-Escudero MP, Boga JA, Bordoy AE, Canut-Blasco A, Carvajal A, Cilla Eguiluz G, Cordón Rodríguez ML, Costa-Alcalde JJ, de Toro M, de Toro Peinado I, Del Pozo JL, Duchêne S, Fernández-Pinero J, Fuster Escrivá B, Gimeno Cardona C, González Galán V, Gonzalo Jiménez N, Hernáez Crespo S, Herranz M, Lepe JA, López-Causapé C, López-Hontangas JL, Martín V, Martró E, Milagro Beamonte A, Montes Ros M, Moreno-Muñoz R, Navarro D, Navarro-Marí JM, Not A, Oliver A, Palop-Borrás B, Parra Grande M, Pedrosa-Corral I, Pérez González MC, Pérez-Lago L, Pérez-Ruiz M, Piñeiro Vázquez L, Rabella N, Rezusta A, Robles Fonseca L, Rodríguez-Villodres Á, Sanbonmatsu-Gámez S, Sicilia J, Soriano A, Tirado Balaguer MD, Torres I, Tristancho A, Marimón JM, SeqCOVID-Spain consortium, Coscolla M, González-Candelas F, Comas I.

    The first wave of the COVID-19 epidemic in Spain was associated with early introductions and fast spread of a dominating genetic variant.

    NATURE GENETICS . 53(10): 1405-1414. Number of citations: 20

    [doi:10.1038/s41588-021-00936-6]

  • Ruiz-Galiana J, Cantón R, De Lucas Ramos P, García-Botella A, García-Lledó A, Gómez-Pavón J, González Del Castillo J, Hernández-Sampelayo T, Martín-Delgado MC, Martín Sánchez FJ, Martínez-Sellés M, Molero García JM, Moreno Guillén S, Rodríguez-Artalejo FJ, Bouza E.

    Vacunación anti-COVID-19: La realidad tras los ensayos clínicos.

    REVISTA ESPANOLA DE QUIMIOTERAPIA . 34(5): 408-418. Number of citations: 1

    [doi:10.37201/req/035.2021]

  • Cantón R, De Lucas Ramos P, García-Botella A, García-Lledó A, Gómez-Pavón J, González Del Castillo J, Hernández-Sampelayo T, Martín-Delgado MC, Martín Sánchez FJ, Martínez-Sellés M, Molero García JM, Moreno Guillén S, Rodríguez-Artalejo FJ, Ruiz-Galiana J, Bouza E.

    New variants of SARS-CoV-2.

    REVISTA ESPANOLA DE QUIMIOTERAPIA . 34(5): 419-428. Number of citations: 35

    [doi:10.37201/req/071.2021]

  • Goldstein, E, Martinez-Garcia, L, Obermeier, M, Glass, A, Krugel, M, Maree, L, Gunson, R, Onelia, F, Pacenti, M, Nelson, KS, Joseph, AM, Palm, MJ, Lucic, D, Marlowe, N, Dhein, J, Reinhardt, B, Pfeifer, K, Galan, JC, Azzato, F.

    Simultaneous identification of Chlamydia trachomatis, Neisseria gonorrhoeae, Mycoplasma genitalium, and Trichomonas vaginalis. multicenter evaluation of the Alinity m STI assay

    Journal of Laboratory Medicine . 45(4-5): 213-223. Number of citations: 1

    [doi:10.1515/labmed-2020-0136]

  • Fluit AC, Bayjanov JR, Aguilar MD, Cantón R, Tunney MM, Elborn JS, van Westreenen M, Ekkelenkamp MB.

    Characterization of clinical Ralstonia strains and their taxonomic position

    ANTONIE VAN LEEUWENHOEK INTERNATIONAL JOURNAL OF GENERAL AND MOLECULAR MICROBIOLOGY . 114(10): 1721-1733. Number of citations: 3

    [doi:10.1007/s10482-021-01637-0]

  • Barquín D, Ndarabu A, Carlos S, Fernández-Alonso M, Rubio-Garrido M, Makonda B, Holguín Á, Reina G.

    HIV-1 diagnosis using dried blood spots from patients in Kinshasa, DRC: a tool to detect misdiagnosis and achieve World Health Organization 2030 targets

    INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES . 111: 253-260. Number of citations: 2

    [doi:10.1016/j.ijid.2021.08.035]

  • Silva-Dias A, Pérez-Viso B, Martins-Oliveira I, Gomes R, Rodrigues AG, Cantón R, Pina-Vaz C.

    Evaluation of FASTinov Ultrarapid Flow Cytometry Antimicrobial Susceptibility Testing Directly from Positive Blood Cultures

    JOURNAL OF CLINICAL MICROBIOLOGY . 59(10): . Number of citations: 4

    [doi:10.1128/JCM.00544-21]

  • Díez-Aguilar M, Ekkelenkamp M, Morosini MI, Huertas N, del Campo R, Zamora J, Fluit AC, Tunney MM, Obrecht D, Bernardini F, Cantón R.

    Anti-biofilm activity of murepavadin against cystic fibrosis Pseudomonas aeruginosa isolates

    JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY . 76(10): 2578-2585. Number of citations: 4

    [doi:10.1093/jac/dkab222]

  • Troyano-Hernaez, Paloma, Reinosa, Roberto, Burgos, Maria Concepcion, Holguin, Africa.

    Update in Natural Antiretroviral Resistance-Associated Mutations Among HIV Type 2 Variants and Discrepancies Across HIV Type 2 Resistance Interpretation Tools

    AIDS RESEARCH AND HUMAN RETROVIRUSES . 37(10): 793-795. Number of citations: 2

    [doi:10.1089/aid.2020.0180]

  • Ruiz-Garbajosa P, Cantón R.

    COVID-19: Impact on prescribing and antimicrobial resistance.

    REVISTA ESPANOLA DE QUIMIOTERAPIA . 34 Suppl 1: 63-68. Number of citations: 3

    [doi:10.37201/req/s01.19.2021]

  • Antequera A, Lopez-Alcalde J, Stallings E, Muriel A, Fernández Félix B, del Campo R, Ponce-Alonso M, Fidalgo P, Halperin AV, Madrid-Pascual O, Álvarez-Díaz N, Solà I, Gordo F, Urrutia G, Zamora J.

    Sex as a prognostic factor for mortality in critically ill adults with sepsis: a systematic review and meta-analysis.

    BMJ open . 11(9): . Number of citations: 2

    [doi:10.1136/bmjopen-2021-048982]

  • Rebelo, Andreia, Mourão J, Freitas, Ana R., Duarte, Barbara, Silveira, Eduarda, Sanchez-Valenzuela, Antonio, Almeida, Agostinho, Baquero, Fernando, Coque, Teresa M., Peixe, Luisa, Antunes, Patricia, Novais, Carla, from the ESCMID Study Group on Food- and Water-borne Infections (EFWISG).

    Diversity of metal and antibiotic resistance genes in Enterococcus spp. from the last century reflects multiple pollution and genetic exchange among phyla from overlapping ecosystems

    SCIENCE OF THE TOTAL ENVIRONMENT . 787: 147548-147548. Number of citations: 9

    [doi:10.1016/j.scitotenv.2021.147548]