Aptamers

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  • Frezza V, Pinto-Díez C, Fernández G, Soto M, Martín ME, García-Sacristán A, González VM.

    DNA aptamers targeting Leishmania infantum H3 protein as potential diagnostic tools.

    ANALYTICA CHIMICA ACTA . 1107: 155-163.

    [doi:10.1016/j.aca.2020.02.012]

  • Vera-Puente O, Rodriguez-Antolin C, Salgado-Figueroa A, Michalska P, Pernia O, Reid BM, Rosas R, Garcia-Guede A, SacristÁn S, Jimenez J, Esteban-Rodriguez I, Martin ME, Sellers TA, León R, Gonzalez VM, De Castro J, Ibanez de Caceres I.

    MAFG is a potential therapeutic target to restore chemosensitivity in cisplatin-resistant cancer cells by increasing reactive oxygen species.

    TRANSLATIONAL RESEARCH . 200: 1-17. Number of citations: 3

    [doi:10.1016/j.trsl.2018.06.005]

  • Chonco L, Fernández G, Kalhapure R, Hernáiz MJ, García-Oliva C, Gonzalez VM, Martín ME, Govender T, Parboosing R.

    Novel DNA Aptamers Against CCL21 Protein: Characterization and Biomedical Applications for Targeted Drug Delivery to T Cell-Rich Zones.

    NUCLEIC ACID THERAPEUTICS . 28(4): 242-251. Number of citations: 2

    [doi:10.1089/nat.2017.0689]

  • Fernández G, Moraga A, Cuartero MI, García-Culebras A, Peña-Martínez C, Pradillo JM, Hernández-Jiménez M, Sacristán S, Ayuso MI, Gonzalo-Gobernado R, Fernández-López D, Martín ME, Moro MA, González VM, Lizasoain I.

    TLR4-Binding DNA Aptamers Show a Protective Effect against Acute Stroke in Animal Models.

    MOLECULAR THERAPY . 26(8): 2047-2059. Number of citations: 7

    [doi:10.1016/j.ymthe.2018.05.019]

  • Garde E, Ramírez L, Corvo L, Solana JC, Martín ME, González VM, Gómez-Nieto C, Barral A, Barral-Netto M, Requena JM, Iborra S, Soto M.

    Analysis of the Antigenic and Prophylactic Properties of the Leishmania Translation Initiation Factors eIF2 and eIF2B in Natural and Experimental Leishmaniasis.

    FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY . 8: 112-112. Number of citations: 4

    [doi:10.3389/fcimb.2018.00112]

  • Pinto-Díez C, García-Recio EM, Pérez-Morgado MI, García-Hernández M, Sanz-Criado L, Sacristán S, Toledo-Lobo MV, Pérez-Mies B, Esteban-Rodríguez I, Pascual A, Garcia-Villanueva M, Martínez-Jañez N, González VM, Martín ME.

    Increased expression of MNK1b, the spliced isoform of MNK1, predicts poor prognosis and is associated with triple-negative breast cancer.

    Oncotarget . 9(17): 13501-13516.

    [doi:10.18632/oncotarget.24417]

  • Sanmartín-Salinas P, Toledo-Lobo MV, Noguerales-Fraguas F, Fernández-Contreras ME, Guijarro LG.

    Overexpression of insulin receptor substrate-4 is correlated with clinical staging in colorectal cancer patients.

    JOURNAL OF MOLECULAR HISTOLOGY . 49(1): 39-49. Number of citations: 3

    [doi:10.1007/s10735-017-9745-0]

  • Moreno E, Schwartz J, Calvo A, Blanco L, Larrea E, Irache JM, Sanmartín C, Coulman SA, Soto M, Birchall JC, Espuelas S.

    Skin vaccination using microneedles coated with a plasmid DNA cocktail encoding nucleosomal histones of Leishmania spp.

    INTERNATIONAL JOURNAL OF PHARMACEUTICS . 533(1): 236-244. Number of citations: 11

    [doi:10.1016/j.ijpharm.2017.09.055]

  • Casado S, Lobo MDVT, Paíno CL.

    Dynamics of plasma membrane surface related to the release of extracellular vesicles by mesenchymal stem cells in culture.

    SCIENTIFIC REPORTS . 7(1): 6767-6767. Number of citations: 6

    [doi:10.1038/s41598-017-07265-x]

  • Solana JC, Ramírez L, Corvo L, de Oliveira CI, Barral-Netto M, Requena JM, Iborra S, Soto M.

    Vaccination with a Leishmania infantum HSP70-II null mutant confers long-term protective immunity against Leishmania major infection in two mice models.

    PLOS NEGLECTED TROPICAL DISEASES . 11(5): e0005644. Number of citations: 9

    [doi:10.1371/journal.pntd.0005644]

  • Martins VT, Lage DP, Duarte MC, Carvalho AM, Costa LE, Mendes TA, Vale DL, Menezes-Souza D, Roatt BM, Tavares CA, Soto M, Coelho EA.

    A recombinant fusion protein displaying murine and human MHC class I- and II-specific epitopes protects against Leishmania amazonensis infection.

    CELLULAR IMMUNOLOGY . 313: 32-42. Number of citations: 8

    [doi:10.1016/j.cellimm.2016.12.008]

  • Vaz Salgado MA, Soto M, Reguero ME, Muñoz G, Cabañero A, Gallego I, Resano S, Longo F, Madariaga A, Gomez A, Carrato A.

    Clinical behavior of solitary fibrous tumor: a retrospective review of 30 patients.

    CLINICAL & TRANSLATIONAL ONCOLOGY . 19(3): 357-363. Number of citations: 2

    [doi:10.1007/s12094-016-1536-7]

  • Román ID, Cano-Martínez D, Lobo MV, Fernández-Moreno MD, Hernández-Breijo B, Sacristán S, Sanmartín-Salinas P, Monserrat J, Gisbert JP, Guijarro LG.

    Infliximab therapy reverses the increase of allograft inflammatory factor-1 in serum and colonic mucosa of rats with inflammatory bowel disease.

    Biomarkers . 22(2): 133-144. Number of citations: 8

    [doi:10.1080/1354750X.2016.1252950]

  • Martins VT, Duarte MC, Lage DP, Costa LE, Carvalho AM, Mendes TA, Roatt BM, Menezes-Souza D, Soto M, Coelho EA.

    A recombinant chimeric protein composed of human and mice-specific CD4(+) and CD8(+) T-cell epitopes protects against visceral leishmaniasis.

    PARASITE IMMUNOLOGY . 39(1): . Number of citations: 17

    [doi:10.1111/pim.12359]

  • González VM, Martín ME, Fernández G, García-Sacristán A.

    Use of Aptamers as Diagnostics Tools and Antiviral Agents for Human Viruses.

    Pharmaceuticals (Basel, Switzerland) . 9(4): . Number of citations: 21

    [doi:10.3390/ph9040078]

  • Iborra S, Martínez-López M, Cueto FJ, Conde-Garrosa R, Del Fresno C, Izquierdo HM, Abram CL, Mori D, Campos-Martín Y, Reguera RM, Kemp B, Yamasaki S, Robinson MJ, Soto M, Lowell CA, Sancho D.

    Leishmania Uses Mincle to Target an Inhibitory ITAM Signaling Pathway in Dendritic Cells that Dampens Adaptive Immunity to Infection

    Immunity . 45(4): 788-801. Number of citations: 36

    [doi:10.1016/j.immuni.2016.09.012]

  • Genes CM, de Lucio H, González VM, Sánchez-Murcia PA, Rico E, Gago F, Fasel N, Jiménez-Ruiz A.

    A functional BH3 domain in an aquaporin from Leishmania infantum.

    Cell death discovery . 2: 16043-16043.

    [doi:10.1038/cddiscovery.2016.43]

  • Duarte MC, Lage DP, Martins VT, Chávez-Fumagalli MA, Roatt BM, Menezes-Souza D, Goulart LR, Soto M, Tavares CA, Coelho EA.

    Recent updates and perspectives on approaches for the development of vaccines against visceral leishmaniasis

    REVISTA DA SOCIEDADE BRASILEIRA DE MEDICINA TROPICAL . 49(4): 398-407. Number of citations: 21

    [doi:10.1590/0037-8682-0120-2016]