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Translational Haematology

Our Translational Hematology group was created with the aim of generating knowledge in the field of hematology and collaborating with other groups for the implementation of projects. Our activity is based on a broad portfolio of clinical trials, basic research projects and registry studies. The area of ​​knowledge in which we focus is the study of the immune system and its relationship with oncohematological diseases and their infectious complications, cell therapy, study of the adverse effects of drugs and optimization in obtaining and using blood components in Transfusion Therapy

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Only original articles, editorials, guidelines.

  • Martínez-López J, De la Cruz J, Gil-Manso R, Alegre A, Ortiz J, Llamas P, Martínez Y, Hernández-Rivas JÁ, González-Gascón I, Benavente C, Estival Monteliu P, Jiménez-Yuste V, Canales M, Bastos M, Kwon M, Valenciano S, Callejas-Charavia M, López-Jiménez J, Herrera P, Duarte R, Núñez Martín-Buitrago L, Sanchez Godoy P, Jacome Yerovi C, Martínez-Barranco P, García Roa M, Escolano Escobar C, Matilla A, Rosado Sierra B, Aláez-Usón MC, Quiroz-Cervantes K, Martínez-Chamorro C, Pérez-Oteyza J, Martos-Martinez R, Herráez R, González-Santillana C, Del Campo JF, Alonso A, de la Fuente A, Pascual A, Bustelos-Rodriguez R, Sebrango A, Ruiz E, Marcheco-Pupo EA, Grande C, Cedillo Á, Lumbreras C, Arroyo Barea A, Casas-Rojo JM, Calbacho M, Diez-Martín JL, García-Suárez J.

    COVID-19 Severity and Survival over Time in Patients with Hematologic Malignancies: A Population-Based Registry Study.

    Cancers . 15(5): . Number of citations: 2

    [doi:10.3390/cancers15051497]

  • Bouza E, Martin M, Alés JE, Aragonés N, Barragán B, de la Cámara R, Del Pozo JL, García-Gutiérrez V, García-Sanz R, Gracia D, Guillem V, Jiménez-Yuste V, Martin-Delgado MC, Martínez J, López R, Rodríguez-Lescure A, Ruiz Galiana J, Sureda AM, Tejerina-Picado F, Trilla A, Zapatero A, Palomo E, San-Miguel J.

    Impact of the COVID-19 pandemic on the diagnosis and treatment of onco-hematologic patients: a discussion paper.

    REVISTA ESPANOLA DE QUIMIOTERAPIA . 36(1): 1-25.

    [doi:10.37201/req/087.2022]

  • Pérez-Lamas L, Luna A, Boque C, Xicoy B, Giraldo P, Pérez López R, Ruiz Nuño C, De Las Heras N, Mora Casterá E, López Marín J, Segura Díaz A, Gómez V, Vélez Tenza P, Sierra Pacho M, Vera Goñi JA, Moreno Vega M, Alvarez-Larrán A, Cortés M, Pérez Encinas M, Carrascosa Mastell P, Angona A, Rosell A, Lakhwani S, Colorado M, Ramila E, Cervero C, Cuevas B, Villalón Blanco L, de Paz R, Paz Coll A, Fernández MJ, Felipe Casado L, Alonso-Domínguez JM, Anguita Arance MM, Salamanca Cuenca A, Jiménez-Velasco A, Prendes SO, Santaliestra M, Lis Chulvi MJ, Hernández-Boluda JC, García-Gutiérrez V.

    Toxicity of Asciminib in Real Clinical Practice: Analysis of Side Effects and Cross-Toxicity with Tyrosine Kinase Inhibitors

    Cancers . 15(4): .

    [doi:10.3390/cancers15041045]

  • Fortún J, Mateos M, de la Pedrosa EG, Soriano C, Pestaña D, Palacios J, López J, Moreno S, Covid-Team.

    Invasive Pulmonary Aspergillosis in Patients with and without SARS-CoV-2 Infection

    JOURNAL OF FUNGI . 9(2): . Number of citations: 3

    [doi:10.3390/jof9020130]

  • Cruz D, Rodríguez-Romanos R, González-Bartulos M, García-Cadenas I, de la Cámara R, Heras I, Buño I, Santos N, Lloveras N, Velarde P, Tuset E, Martínez C, González M, Sanz GF, Ferrá C, Sampol A, Coll R, Pérez-Simón JA, López-Jiménez J, Jurado M, Gallardo D.

    LAG3 genotype of the donor and clinical outcome after allogeneic transplantation from HLA-identical sibling donors

    Frontiers in immunology . 14: 1066393-1066393.

    [doi:10.3389/fimmu.2023.1066393]

  • Casado-Fernández G, Corona M, Torres M, Saez AJ, Ramos-Martín F, Manzanares M, Vigón L, Mateos E, Pozo F, Casas I, García-Gutierrez V, Rodríguez-Mora S, Coiras M.

    Sustained Cytotoxic Response of Peripheral Blood Mononuclear Cells from Unvaccinated Individuals Admitted to the ICU Due to Critical COVID-19 Is Essential to Avoid a Fatal Outcome.

    INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH . 20(3): .

    [doi:10.3390/ijerph20031947]

  • Piñana JL, Vazquez L, Calabuig M, López-Corral L, Martin-Martin G, Villalon L, Sanz-Linares G, Conesa-Garcia V, Sanchez-Salinas A, Gago B, Facal A, Risco-Gálvez I, Olave MT, Espigado I, Lopez-Jimenez J, Hernández-Rivas JÁ, Avendaño-Pita A, Arroyo I, Ferrer E, García-Cadenas I, González-Santillana C, Roldán-Pérez A, Ferrer B, Guerreiro M, Suarez-Lledó M, Camara A, Campos-Beltrán D, Navarro D, Cedillo Á, Sureda A, Solano C, Martino R.

    One-year breakthrough SARS-CoV-2 infection and correlates of protection in fully vaccinated hematological patients

    BLOOD CANCER JOURNAL . 13(1): 8-8. Number of citations: 9

    [doi:10.1038/s41408-022-00778-3]

  • Harrison C, Yacoub A, Scott B, Mead A, Gerds AT, Kiladjian JJ, Mesa R, Egyed M, Scheid C, Gutierrez VG, O'Sullivan J, Buckley S, Kanellopoulos K, Mascarenhas J.

    Long-term treatment with pacritinib on a compassionate use basis in patients with advanced myelofibrosis.

    Haematologica . : .

    [doi:10.3324/haematol.2022.282089]

  • Meijón Ortigueira MDM, Álvarez-Román MT, De La Corte Rodríguez H, Butta Coll N, Jiménez-Yuste V.

    Long-term impact of primary prophylaxis on joint status in patients with severe hemophilia A

    Research And Practice In Thrombosis And Haemostasis . 7(1): 100005-100005. Number of citations: 2

    [doi:10.1016/j.rpth.2022.100005]

  • Sargas, Claudia, Ayala, Rosa, Larrayoz, Maria Jose, Chillon, Maria Carmen, Carrillo-Cruz, Estrella, Bilbao-Sieyro, Cristina, Prados de la Torre, Esther, Martinez-Cuadron, David, Rodriguez-Veiga, Rebeca, Boluda, Blanca, Gil, Cristina, Bernal, Teresa, Bergua, Juan Miguel, Algarra, Lorenzo, Tormo, Mar, Martinez-Sanchez, Pilar, Soria, Elena, Serrano, Josefina, Alonso-Dominguez, Juan Manuel, Garcia-Boyero, Raimundo, Amigo, Maria Luz, Herrera-Puente, Pilar, Sayas, Maria Jose, Lavilla-Rubira, Esperanza, Martinez-Lopez, Joaquin, Calasanz, Maria Jose, Garcia-Sanz, Ramon, Perez-Simon, Jose Antonio, Gomez-Casares, Maria Teresa, Sanchez-Garcia, Joaquin, Barragan, Eva, Montesinos, Pau, On Behalf Of Pethema Group.

    Molecular Landscape and Validation of New Genomic Classification in 2668 Adult AML Patients: Real Life Data from the PETHEMA Registry

    Cancers . 15(2): . Number of citations: 6

    [doi:10.3390/cancers15020438]

  • Pascual Izquierdo MC, Mingot-Castellano ME, Kerguelen Fuentes AE, García-Arroba Peinado J, Cid J, Jiménez M, Valcarcel D, Gomez-Segui I, de la Rubia J, Martin P, Goterris R, Hernández-Mateo LM, Tallón Ruiz I, Varea S, Fernández-Docampp M, García-Muñoz N, Vara M, Fernández Zarzoso M, García-Candel F, Paciello ML, García-García I, Zalba S, Campuzano Saavedra V, Garcia-Gala JMM, Vidan J, Moreno G, Lopez Lorenzo JL, González Arias E, Freiría C, Solé M, Ávila Idrovo LF, Hernández Castellet JC, Cruz N, Lavilla E, Pérez-Montaña A, Atucha JA, Moreno Beltrán ME, Romero Macías JR, Salinas Argente R, Del Rio-Garma J.

    Real-world effectiveness of caplacizumab vs standard of care in immune thrombotic thrombocytopenic purpura.

    Blood Advances . 6(24): 6219-6227. Number of citations: 9

    [doi:10.1182/bloodadvances.2022008028]

  • Nadarajah R, Ludman P, Appelman Y, Brugaletta S, Budaj A, Bueno H, Huber K, Kunadian V, Leonardi S, Lettino M, Milasinovic D, Gale CP.

    Cohort profile: the ESC EURObservational Research Programme Non-ST-segment elevation myocardial infraction (NSTEMI) Registry.

    EUROPEAN HEART JOURNAL-QUALITY OF CARE AND CLINICAL OUTCOMES . 9(1): 8-15.

    [doi:10.1093/ehjqcco/qcac067]

  • Ayala R, Carreño-Tarragona G, Barragán E, Boluda B, Larráyoz MJ, Chillón MC, Carrillo-Cruz E, Bilbao C, Sánchez-García J, Bernal T, Martinez-Cuadron D, Gil C, Serrano J, Rodriguez-Medina C, Bergua J, Pérez-Simón JA, Calbacho M, Alonso-Domínguez JM, Labrador J, Tormo M, Amigo ML, Herrera-Puente P, Rapado I, Sargas C, Vazquez I, Calasanz MJ, Gomez-Casares T, García-Sanz R, Sanz MA, Martínez-López J, Montesinos P.

    Impact of FLT3-ITD Mutation Status and Its Ratio in a Cohort of 2901 Patients Undergoing Upfront Intensive Chemotherapy: A PETHEMA Registry Study

    Cancers . 14(23): . Number of citations: 4

    [doi:10.3390/cancers14235799]

  • Barbui T, Carobbio A, Ghirardi A, Iurlo A, Sobas MA, Elli EM, Rumi E, De Stefano V, Lunghi F, Marchetti M, Daffini R, Gasior Kabat M, Cuevas B, Fox ML, Andrade-Campos MM, Palandri F, Guglielmelli P, Benevolo G, Harrison C, Foncillas MA, Bonifacio M, Alvarez-Larran A, Kiladjian JJ, Bolaños Calderón E, Patriarca A, Quiroz Cervantes K, Griesshammer M, Garcia-Gutierrez V, Marin Sanchez A, Magro Mazo E, Carli G, Hernandez-Boluda JC, Osorio S, Carreno-Tarragona G, Sagues Serrano M, Kusec R, Navas Elorza B, Angona A, Xicoy Cirici B, Lopez Abadia E, Koschmieder S, Cattaneo D, Bucelli C, Cichocka E, de Nalecz AK, Cavalca F, Borsani O, Betti S, Bellini M, Curto-Garcia N, Rambaldi A, Vannucchi AM.

    Determinants of early triage for hospitalization in myeloproliferative neoplasm (MPN) patients with COVID-19

    AMERICAN JOURNAL OF HEMATOLOGY . 97(12): 470-473. Number of citations: 3

    [doi:10.1002/ajh.26732]

  • Villar S, Ariceta B, Agirre X, Urribarri AD, Ayala R, Martínez-Cuadrón D, Bergua JM, Vives S, Algarra L, Tormo M, Martínez P, Serrano J, Simoes C, Herrera P, Calasanz MJ, Alfonso-Piérola A, Paiva B, Martínez-López J, San Miguel JF, Prósper F, Montesinos P.

    The transcriptomic landscape of elderly acute myeloid leukemia identifies B7H3 and BANP as a favorable signature in high-risk patients

    Frontiers in Oncology . 12: 1054458-1054458.

    [doi:10.3389/fonc.2022.1054458]

  • García-Abellás P, Ferrer Gómez A, Bueno Sacristán D, Piris Villaespesa M, Talavera Yagüe M, Reguero Callejas ME, García-Cosío M.

    Lymphoplasmacytic lymphoma and marginal zone lymphoma involving bone marrow: A diagnostic dilemma. Useful clinicopathological features to accurate the diagnosis.

    Ejhaem . 3(4): 1181-1187.

    [doi:10.1002/jha2.573]

  • Torres M, Corona M, Rodríguez-Mora S, Casado-Fernández G, Zurdo-Castronuño A, Mateos E, Ramos-Martín F, Sánchez-Menéndez C, Murciano-Antón MA, García-Pérez J, Alcamí J, Pérez-Olmeda M, Coiras M, López-Jiménez J, García-Gutiérrez V, On Behalf Of The Multidisciplinary Group Of Study Of Covid-Mgs-Covid.

    Strong Humoral but Not Cellular Immune Responses against SARS-CoV-2 in Individuals with Oncohematological Disease Who Were Treated with Rituximab before Receiving a Vaccine Booster

    Cancers . 14(22): .

    [doi:10.3390/cancers14225537]

  • Ortuzar A, Fox ML, Vera JA, Lorenzo Vizcaya Á, Marín Sánchez A, Llopis Calatayud I, Carbonell S, Álvarez-Larrán A, Mata Serna R, Marco Buades JE, Quiroz Cervantes K, Martínez Hellín Á, Blum Domínguez A, Caballero Navarro G, Cáceres Sansaloni A, Guerrero Fernández L, Muñoz Linares C, Gasior Kabat M, Pérez López R, Fernández Rodríguez Á, Martínez Bilbao C, Cobo Rodríguez MT, Díaz Á, Durán MA, Santaliestra Tomas M, García-Gutierrez V, Magro Mazo E, Hernández-Boluda JC, Segura A, Raya JM, Navas Elorza B, Osorio S.

    Philadelphia-negative chronic myeloproliferative neoplasm follow-up: when the phone rings. Changes during the COVID-19 pandemic and patient satisfaction. Experience in 30 health centers in Spain.

    ANNALS OF HEMATOLOGY . 102(2): 447-456.

    [doi:10.1007/s00277-022-05044-x]