Cancer stem cells and fibroinflammatory microenvironment

Search for publications

Only original articles, editorials, guidelines.

  • Lerma L, Muñoz AL, García Utrilla R, Sainz B, Lim F, Tabarés E, Gómez-Sebastián S.

    Partial complementation between the immediate early proteins ICP4 of herpes simplex virus type 1 and IE180 of pseudorabies virus.

    VIRUS RESEARCH . 279: 197896-197896.

    [doi:10.1016/j.virusres.2020.197896]

  • Alcala S, Mayoral-Varo V, Ruiz-Canas L, Lopez-Gil JC, Heeschen C, Martin-Perez J, Sainz B Jr.

    Targeting SRC Kinase Signaling in Pancreatic Cancer Stem Cells.

    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES . 21(20): .

    [doi:10.3390/ijms21207437]

  • Cabezas-Sainz P, Pensado-Lopez A, Sainz B Jr, Sanchez L.

    Modeling Cancer Using Zebrafish Xenografts: Drawbacks for Mimicking the Human Microenvironment.

    Cells . 9(9): .

    [doi:10.3390/cells9091978]

  • Pajuelo-Lozano N, Alcalá S, Sainz B, Perona R, Sanchez-Perez I.

    Targeting MAD2 modulates stemness and tumorigenesis in human Gastric Cancer cell lines.

    THERANOSTICS . 10(21): 9601-9618.

    [doi:10.7150/thno.49270]

  • Cash TP, Alcalá S, Rico-Ferreira MDR, Hernández-Encinas E, García J, Albarrán MI, Valle S, Muñoz J, Martínez-González S, Blanco-Aparicio C, Pastor J, Serrano M, Sainz B.

    Induction of Lysosome Membrane Permeabilization as a Therapeutic Strategy to Target Pancreatic Cancer Stem Cells.

    Cancers . 12(7): .

    [doi:10.3390/cancers12071790]

  • Frappart PO, Walter K, Gout J, Beutel AK, Morawe M, Arnold F, Breunig M, Barth TF, Marienfeld R, Schulte L, Ettrich T, Hackert T, Svinarenko M, Rösler R, Wiese S, Wiese H, Perkhofer L, Müller M, Lechel A, Sainz B, Hermann PC, Seufferlein T, Kleger A.

    Pancreatic cancer-derived organoids - a disease modeling tool to predict drug response.

    UNITED EUROPEAN GASTROENTEROLOGY JOURNAL . 8(5): 594-606. Number of citations: 8

    [doi:10.1177/2050640620905183]

  • Alcalá S, Sancho P, Martinelli P, Navarro D, Pedrero C, Martín-Hijano L, Valle S, Earl J, Rodríguez-Serrano M, Ruiz-Cañas L, Rojas K, Carrato A, García-Bermejo L, Fernández-Moreno MÁ, Hermann PC, Sainz B.

    ISG15 and ISGylation is required for pancreatic cancer stem cell mitophagy and metabolic plasticity.

    NATURE COMMUNICATIONS . 11(1): 2682-2682.

    [doi:10.1038/s41467-020-16395-2]

  • Martin-Hijano L, Sainz B.

    The Interactions Between Cancer Stem Cells and the Innate Interferon Signaling Pathway.

    Frontiers in immunology . 11: 526-526.

    [doi:10.3389/fimmu.2020.00526]

  • Alcalá S, Sainz B.

    The dark side of radiotherapy-induced cell death in cancer.

    EBioMedicine . 40: 7-8. Number of citations: 1

    [doi:10.1016/j.ebiom.2019.01.047]

  • Schulte LA, López-Gil JC, Sainz B, Hermann PC.

    The Cancer Stem Cell in Hepatocellular Carcinoma.

    Cancers . 12(3): . Number of citations: 3

    [doi:10.3390/cancers12030684]

  • Rodriguez-Aznar E, Wiesmüller L, Sainz B, Hermann PC.

    EMT and Stemness-Key Players in Pancreatic Cancer Stem Cells.

    Cancers . 11(8): 1136. Number of citations: 16

    [doi:10.3390/cancers11081136]

  • D'Errico G, Alonso-Nocelo M, Vallespinos M, Hermann PC, Alcalá S, García CP, Martin-Hijano L, Valle S, Earl J, Cassiano C, Lombardia L, Feliu J, Monti MC, Seufferlein T, García-Bermejo L, Martinelli P, Carrato A, Sainz B.

    Tumor-associated macrophage-secreted 14-3-3? signals via AXL to promote pancreatic cancer chemoresistance.

    Oncogene . 38(27): 5469-5485. Number of citations: 14

    [doi:10.1038/s41388-019-0803-9]

  • Walter K, Tiwary K, Trajkovic-Arsic M, Hidalgo-Sastre A, Dierichs L, Liffers ST, Gu J, Gout J, Schulte LA, Münch J, Seufferlein T, Sainz B, Siveke JT, Rodriguez-Aznar E, Hermann PC.

    MEK Inhibition Targets Cancer Stem Cells and Impedes Migration of Pancreatic Cancer Cells In Vitro and In Vivo .

    STEM CELLS INTERNATIONAL . 2019: 8475389-8475389. Number of citations: 3

    [doi:10.1155/2019/8475389]

  • Alcalá S, Martinelli P, Hermann PC, Heeschen C, Sainz B.

    The Anthrax Toxin Receptor 1 (ANTXR1) Is Enriched in Pancreatic Cancer Stem Cells Derived from Primary Tumor Cultures.

    STEM CELLS INTERNATIONAL . 2019: 1378639-1378639. Number of citations: 3

    [doi:10.1155/2019/1378639]

  • Blasco MT, Navas C, Martín-Serrano G, Graña-Castro O, Lechuga CG, Martín-Díaz L, Djurec M, Li J, Morales-Cacho L, Esteban-Burgos L, Perales-Patón J, Bousquet-Mur E, Castellano E, Jacob HKC, Cabras L, Musteanu M, Drosten M, Ortega S, Mulero F, Sainz B, Dusetti N, Iovanna J, Sánchez-Bueno F, Hidalgo M, Khiabanian H, Rabadán R, Al-Shahrour F, Guerra C, Barbacid M.

    Complete Regression of Advanced Pancreatic Ductal Adenocarcinomas upon Combined Inhibition of EGFR and C-RAF.

    Cancer Cell . 35(4): 573. Number of citations: 15

    [doi:10.1016/j.ccell.2019.03.002]

  • Gout J, Perkhofer L, Morawe M, Arnold F, Ihle M, Biber S, Lange S, Roger E, Kraus JM, Stifter K, Hahn SA, Zamperone A, Engleitner T, Muller M, Walter K, Rodriguez-Aznar E, Sainz B Jr, Hermann PC, Hessmann E, Muller S, Azoitei N, Lechel A, Liebau S, Wagner M, Simeone DM, Kestler HA, Seufferlein T, Wiesmuller L, Rad R, Frappart PO, Kleger A.

    Synergistic targeting and resistance to PARP inhibition in DNA damage repair-deficient pancreatic cancer.

    Gut . : .

    [doi:10.1136/gutjnl-2019-319970]