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Biomarkers and Personalized Approach to Cancer Group (BioPAC)

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  • da Silva IL, Montero-Montero L, Martín-Villar E, Martin-Pérez J, Sainz B, Renart J, Toscano Simões R, Soares Veloso É, Salviano Teixeira C, de Oliveira MC, Ferreira E, Quintanilla M.

    Reduced expression of the murine HLA-G homolog Qa-2 is associated with malignancy, epithelial-mesenchymal transition and stemness in breast cancer cells.

    SCIENTIFIC REPORTS . 7(1): 6276-6276. Number of citations: 8

    [doi:10.1038/s41598-017-06528-x]

  • López-Gómez M, Casado E, Muñoz M, Alcalá S, Moreno-Rubio J, D'Errico G, Jiménez-Gordo AM, Salinas S, Sainz B.

    Current evidence for cancer stem cells in gastrointestinal tumors and future research perspectives.

    CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY . 107: 54-71. Number of citations: 3

    [doi:10.1016/j.critrevonc.2016.08.006]

  • Zagorac S, Alcala S, Fernandez Bayon G, Bou Kheir T, Schoenhals M, González-Neira A, Fernandez Fraga M, Aicher A, Heeschen C, Sainz B.

    DNMT1 Inhibition Reprograms Pancreatic Cancer Stem Cells via Upregulation of the miR-17-92 Cluster

    CANCER RESEARCH . 76(15): 4546-4558. Number of citations: 71

    [doi:10.1158/0008-5472.CAN-15-3268]

  • Sancho P, Alcala S, Usachov V, Hermann PC, Sainz B.

    The ever-changing landscape of pancreatic cancer stem cells.

    Pancreatology . 16(4): 489-496. Number of citations: 19

    [doi:10.1016/j.pan.2016.04.004]

  • Sainz B, Carron E, Vallespinós M, Machado HL.

    Cancer Stem Cells and Macrophages: Implications in Tumor Biology and Therapeutic Strategies

    MEDIATORS OF INFLAMMATION . 2016: 9012369-9012369. Number of citations: 66

    [doi:10.1155/2016/9012369]

  • Cioffi M, Vallespinos-Serrano M, Trabulo SM, Fernandez-Marcos PJ, Firment AN, Vazquez BN, Vieira CR, Mulero F, Camara JA, Cronin UP, Perez M, Soriano J, G Galvez B, Castells-Garcia A, Haage V, Raj D, Megias D, Hahn S, Serrano L, Moon A, Aicher A, Heeschen C.

    MiR-93 Controls Adiposity via Inhibition of Sirt7 and Tbx3

    CELL REPORTS . 12(10): 1594-1605. Number of citations: 79

    [doi:10.1016/j.celrep.2015.08.006]

  • Hohwieler M, Illing A, Hermann PC, Mayer T, Stockmann M, Perkhofer L, Eiseler T, Antony JS, Müller M, Renz S, Kuo CC, Lin Q, Sendler M, Breunig M, Kleiderman SM, Lechel A, Zenker M, Leichsenring M, Rosendahl J, Zenke M, Sainz B, Mayerle J, Costa IG, Seufferlein T, Kormann M, Wagner M, Liebau S, Kleger A.

    Human pluripotent stem cell-derived acinar/ductal organoids generate human pancreas upon orthotopic transplantation and allow disease modelling.

    Gut . : .

    [doi:10.1136/gutjnl-2016-312423]

  • Martinelli P, Carrillo-de Santa Pau E, Cox T, Sainz B, Dusetti N, Greenhalf W, Rinaldi L, Costello E, Ghaneh P, Malats N, Büchler M, Pajic M, Biankin AV, Iovanna J, Neoptolemos J, Real FX.

    GATA6 regulates EMT and tumour dissemination, and is a marker of response to adjuvant chemotherapy in pancreatic cancer.

    Gut . : .

    [doi:10.1136/gutjnl-2015-311256]