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Biomarkers and Personalized Approach to Cancer Group (BioPAC)

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  • López-Gómez M, Casado E, Muñoz M, Alcalá S, Moreno-Rubio J, D'Errico G, Jiménez-Gordo AM, Salinas S, Sainz B.

    Current evidence for cancer stem cells in gastrointestinal tumors and future research perspectives.

    CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY . 107: 54-71. Number of citations: 10

    [doi:10.1016/j.critrevonc.2016.08.006]

  • Zagorac S, Alcala S, Fernandez Bayon G, Bou Kheir T, Schoenhals M, González-Neira A, Fernandez Fraga M, Aicher A, Heeschen C, Sainz B.

    DNMT1 Inhibition Reprograms Pancreatic Cancer Stem Cells via Upregulation of the miR-17-92 Cluster

    CANCER RESEARCH . 76(15): 4546-4558. Number of citations: 95

    [doi:10.1158/0008-5472.CAN-15-3268]

  • Sancho P, Alcala S, Usachov V, Hermann PC, Sainz B.

    The ever-changing landscape of pancreatic cancer stem cells.

    Pancreatology . 16(4): 489-496. Number of citations: 30

    [doi:10.1016/j.pan.2016.04.004]

  • Sainz B, Carron E, Vallespinós M, Machado HL.

    Cancer Stem Cells and Macrophages: Implications in Tumor Biology and Therapeutic Strategies

    MEDIATORS OF INFLAMMATION . 2016: 9012369-9012369. Number of citations: 92

    [doi:10.1155/2016/9012369]

  • Cioffi M, Vallespinos-Serrano M, Trabulo SM, Fernandez-Marcos PJ, Firment AN, Vazquez BN, Vieira CR, Mulero F, Camara JA, Cronin UP, Perez M, Soriano J, G Galvez B, Castells-Garcia A, Haage V, Raj D, Megias D, Hahn S, Serrano L, Moon A, Aicher A, Heeschen C.

    MiR-93 Controls Adiposity via Inhibition of Sirt7 and Tbx3

    Cell Reports . 12(10): 1594-1605. Number of citations: 102

    [doi:10.1016/j.celrep.2015.08.006]

  • Hohwieler M, Illing A, Hermann PC, Mayer T, Stockmann M, Perkhofer L, Eiseler T, Antony JS, Müller M, Renz S, Kuo CC, Lin Q, Sendler M, Breunig M, Kleiderman SM, Lechel A, Zenker M, Leichsenring M, Rosendahl J, Zenke M, Sainz B, Mayerle J, Costa IG, Seufferlein T, Kormann M, Wagner M, Liebau S, Kleger A.

    Human pluripotent stem cell-derived acinar/ductal organoids generate human pancreas upon orthotopic transplantation and allow disease modelling.

    GUT . : . Number of citations: 187

    [doi:10.1136/gutjnl-2016-312423]

  • Martinelli P, Carrillo-de Santa Pau E, Cox T, Sainz B, Dusetti N, Greenhalf W, Rinaldi L, Costello E, Ghaneh P, Malats N, Büchler M, Pajic M, Biankin AV, Iovanna J, Neoptolemos J, Real FX.

    GATA6 regulates EMT and tumour dissemination, and is a marker of response to adjuvant chemotherapy in pancreatic cancer.

    GUT . : . Number of citations: 229

    [doi:10.1136/gutjnl-2015-311256]

  • Guerrero P, Albarrán V, González-Merino C, García de Quevedo C, Sotoca P, Chamorro J, Rosero DI, Barrill A, Alía V, Calvo JC, Moreno J, Pérez de Aguado P, Álvarez-Ballesteros P, San Román M, Serrano JJ, Soria A, Olmedo ME, Saavedra C, Cortés A, Gómez A, Lage Y, Ruiz Á, Ferreiro MR, Longo F, Guerra E, Martínez-Delfrade Í, Garrido P, Gajate P.

    Detrimental effect of an early exposure to antibiotics on the outcomes of immunotherapy in a multi-tumor cohort of patients.

    ONCOLOGIST . : .

    [doi:10.1093/oncolo/oyae284]

  • Biesma NC, Graus MUJE, Cirkel GA, Besselink MG, de Groot JWB, Koerkamp BG, Herbschleb KH, Los M, Verdonk RC, Wilmink JW, Cervantes A, Valle JW, Valkenburg-van Iersel LBJ, Froeling FEM, Molenaar IQ, Daamen LA, de Vos-Geelen J, van Santvoort HC.

    Perspectives of the medical oncologist regarding adjuvant chemotherapy for pancreatic cancer: An international expert survey and case vignette study.

    EJSO . 51(3): 109544-109544. Number of citations: 7

    [doi:10.1016/j.ejso.2024.109544]

  • Rodriguez Salas N, de la Haba-Rodriguez J, Ferragut Lloret F, Vaz Salgado MA, Oré Arce M, Cardeña Gutiérrez A, Beato Zambrano C, Rodríguez Alonso RM, López López R, García-Donas Jiménez J.

    SEOM-GETTHI clinical guideline for the practical management of molecular platforms (update 2026).

    Clinical & Translational Oncology . : .

    [doi:10.1007/s12094-026-04520-4]

  • Morilla I, Caviedes E, Gironés Sarrió R, López de San Vicente Hernández B, Luque Caro N, Del Barco S, Cano JM, Vaz-Salgado MÁ.

    Management of glioblastoma in the elderly.

    Clinical & Translational Oncology . : .

    [doi:10.1007/s12094-026-04546-8]

  • Campa D, Rizzato C, Kataki A, Greenhalf W, Paiella S, Earl J.

    Predicting pancreatic cancer in high-risk individuals and in the general population: how long is the road yet?

    REVISTA ESPANOLA DE ENFERMEDADES DIGESTIVAS . : .

    [doi:10.17235/reed.2026.12183/2026]