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Cancer stem cells and fibroinflammatory microenvironment

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Only original articles, editorials, guidelines.

  • Lerma L, Muñoz AL, García Utrilla R, Sainz B, Lim F, Tabarés E, Gómez-Sebastián S.

    Partial complementation between the immediate early proteins ICP4 of herpes simplex virus type 1 and IE180 of pseudorabies virus.

    VIRUS RESEARCH . 279: 197896-197896.

    [doi:10.1016/j.virusres.2020.197896]

  • Rodriguez-Aznar E, Wiesmüller L, Sainz B, Hermann PC.

    EMT and Stemness-Key Players in Pancreatic Cancer Stem Cells.

    Cancers . 11(8): 1136. Number of citations: 4

    [doi:10.3390/cancers11081136]

  • D'Errico G, Alonso-Nocelo M, Vallespinos M, Hermann PC, Alcalá S, García CP, Martin-Hijano L, Valle S, Earl J, Cassiano C, Lombardia L, Feliu J, Monti MC, Seufferlein T, García-Bermejo L, Martinelli P, Carrato A, Sainz B.

    Tumor-associated macrophage-secreted 14-3-3? signals via AXL to promote pancreatic cancer chemoresistance.

    Oncogene . 38(27): 5469-5485. Number of citations: 6

    [doi:10.1038/s41388-019-0803-9]

  • Walter K, Tiwary K, Trajkovic-Arsic M, Hidalgo-Sastre A, Dierichs L, Liffers ST, Gu J, Gout J, Schulte LA, Münch J, Seufferlein T, Sainz B, Siveke JT, Rodriguez-Aznar E, Hermann PC.

    MEK Inhibition Targets Cancer Stem Cells and Impedes Migration of Pancreatic Cancer Cells In Vitro and In Vivo .

    STEM CELLS INTERNATIONAL . 2019: 8475389-8475389. Number of citations: 2

    [doi:10.1155/2019/8475389]

  • Alcalá S, Martinelli P, Hermann PC, Heeschen C, Sainz B.

    The Anthrax Toxin Receptor 1 (ANTXR1) Is Enriched in Pancreatic Cancer Stem Cells Derived from Primary Tumor Cultures.

    STEM CELLS INTERNATIONAL . 2019: 1378639-1378639. Number of citations: 1

    [doi:10.1155/2019/1378639]

  • Blasco MT, Navas C, Martín-Serrano G, Graña-Castro O, Lechuga CG, Martín-Díaz L, Djurec M, Li J, Morales-Cacho L, Esteban-Burgos L, Perales-Patón J, Bousquet-Mur E, Castellano E, Jacob HKC, Cabras L, Musteanu M, Drosten M, Ortega S, Mulero F, Sainz B, Dusetti N, Iovanna J, Sánchez-Bueno F, Hidalgo M, Khiabanian H, Rabadán R, Al-Shahrour F, Guerra C, Barbacid M.

    Complete Regression of Advanced Pancreatic Ductal Adenocarcinomas upon Combined Inhibition of EGFR and C-RAF.

    Cancer Cell . 35(4): 573. Number of citations: 8

    [doi:10.1016/j.ccell.2019.03.002]

  • Alcalá S, Sainz B.

    The dark side of radiotherapy-induced cell death in cancer.

    EBioMedicine . 40: 7-8.

    [doi:10.1016/j.ebiom.2019.01.047]

  • Hermann PC, Sainz B.

    Pancreatic cancer stem cells: A state or an entity?

    Seminars in cancer biology . 53: 223-231. Number of citations: 14

    [doi:10.1016/j.semcancer.2018.08.007]

  • Friederich MW, Timal S, Powell CA, Dallabona C, Kurolap A, Palacios-Zambrano S, Bratkovic D, Derks TGJ, Bick D, Bouman K, Chatfield KC, Damouny-Naoum N, Dishop MK, Falik-Zaccai TC, Fares F, Fedida A, Ferrero I, Gallagher RC, Garesse R, Gilberti M, González C, Gowan K, Habib C, Halligan RK, Kalfon L, Knight K, Lefeber D, Mamblona L, Mandel H, Mory A, Ottoson J, Paperna T, Pruijn GJM, Rebelo-Guiomar PF, Saada A, Sainz B, Salvemini H, Schoots MH, Smeitink JA, Szukszto MJ, Ter Horst HJ, van den Brandt F, van Spronsen FJ, Veltman JA, Wartchow E, Wintjes LT, Zohar Y, Fernández-Moreno MA, Baris HN, Donnini C, Minczuk M, Rodenburg RJ, Van Hove JLK.

    Pathogenic variants in glutamyl-tRNA Gln amidotransferase subunits cause a lethal mitochondrial cardiomyopathy disorder.

    NATURE COMMUNICATIONS . 9(1): 4065-4065. Number of citations: 7

    [doi:10.1038/s41467-018-06250-w]

  • Zagorac, Sladjana, Garcia-Bermejo, Laura, Sainz, Bruno, Jr..

    The Epigenetic Landscape of Pancreatic Cancer Stem Cells

    Epigenomes . 2(2): 10.

    [doi:10.3390/epigenomes2020010]

  • Alguacil-Núñez C, Ferrer-Ortiz I, García-Verdú E, López-Pirez P, Llorente-Cortijo IM, Sainz B.

    Current perspectives on the crosstalk between lung cancer stem cells and cancer-associated fibroblasts.

    CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY . 125: 102-110. Number of citations: 7

    [doi:10.1016/j.critrevonc.2018.02.015]

  • González I, Earl J, Fernández LJ, Sainz B, Pinto A, Monge R, Alcalá S, Castillejo A, Soto JL, Carrato A.

    A Label Free Disposable Device for Rapid Isolation of Rare Tumor Cells from Blood by Ultrasounds.

    MICROMACHINES . 9(3): 129. Number of citations: 7

    [doi:10.3390/mi9030129]

  • Djurec M, Graña O, Lee A, Troulé K, Espinet E, Cabras L, Navas C, Blasco MT, Martín-Díaz L, Burdiel M, Li J, Liu Z, Vallespinós M, Sanchez-Bueno F, Sprick MR, Trumpp A, Sainz B, Al-Shahrour F, Rabadan R, Guerra C, Barbacid M.

    Saa3 is a key mediator of the protumorigenic properties of cancer-associated fibroblasts in pancreatic tumors.

    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA . 115(6): 1147-1156. Number of citations: 24

    [doi:10.1073/pnas.1717802115]

  • Valle S, Martin-Hijano L, Alcalá S, Alonso-Nocelo M, Sainz B.

    The Ever-Evolving Concept of the Cancer Stem Cell in Pancreatic Cancer.

    Cancers . 10(2): 33. Number of citations: 33

    [doi:10.3390/cancers10020033]

  • D'Errico G, Machado HL, Sainz B.

    A current perspective on cancer immune therapy: step-by-step approach to constructing the magic bullet.

    Clinical And Translational Medicine . 6(1): 3-3. Number of citations: 29

    [doi:10.1186/s40169-016-0130-5]

  • da Silva IL, Montero-Montero L, Martín-Villar E, Martin-Pérez J, Sainz B, Renart J, Toscano Simões R, Soares Veloso É, Salviano Teixeira C, de Oliveira MC, Ferreira E, Quintanilla M.

    Reduced expression of the murine HLA-G homolog Qa-2 is associated with malignancy, epithelial-mesenchymal transition and stemness in breast cancer cells.

    SCIENTIFIC REPORTS . 7(1): 6276-6276. Number of citations: 4

    [doi:10.1038/s41598-017-06528-x]

  • López-Gómez M, Casado E, Muñoz M, Alcalá S, Moreno-Rubio J, D'Errico G, Jiménez-Gordo AM, Salinas S, Sainz B.

    Current evidence for cancer stem cells in gastrointestinal tumors and future research perspectives.

    CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY . 107: 54-71. Number of citations: 2

    [doi:10.1016/j.critrevonc.2016.08.006]

  • Zagorac S, Alcala S, Fernandez Bayon G, Bou Kheir T, Schoenhals M, González-Neira A, Fernandez Fraga M, Aicher A, Heeschen C, Sainz B.

    DNMT1 Inhibition Reprograms Pancreatic Cancer Stem Cells via Upregulation of the miR-17-92 Cluster

    CANCER RESEARCH . 76(15): 4546-4558. Number of citations: 40

    [doi:10.1158/0008-5472.CAN-15-3268]