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Biomarkers and therapeutics targets

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  • Bara-Ledesma N, Viteri-Noel A, Lopez Rodriguez M, Stamatakis K, Fabregate M, Vazquez-Santos A, Gomez Del Olmo V.

    Advances in Gene Therapy for Rare Diseases: Targeting Functional Haploinsufficiency Through AAV and mRNA Approaches

    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES . 26(2): . Number of citations: 16

    [doi:10.3390/ijms26020578]

  • Hewitt E, Bouche G, Alencar AC, Bigelsen SJ, Radu R, Stoyanova-Beninska V, Carrato A, Valsecchi F, Soler Cantón A, van der Meer HG, García Bermejo ML, Budillon A, Cardone L, Rooman I, Platteeuw H, Baijet J, Fuchs C.

    Drug Repurposing in Pancreatic Cancer: A Multi-Stakeholder Perspective to Improve Treatment Options for Pancreatic Cancer Patients

    Cancer Management and Research . 17: 429-440. Number of citations: 2

    [doi:10.2147/CMAR.S483151]

  • Ciérvide R, Manchón R, Ángel D, Quiles B, Rodríguez G, Veiras M, Blanco J, Diaz FM, Del Portillo EG, Monroy JL, Larrea L, Expósito J, Aristu J, Benavente S, Corrales-García E, Prieto C, García ME, Payano S, Perez MJ, Miguel IS, de la Pinta C, Díaz L, Mascias VM, Villarreal CLM, López M, Martínez FJ, Peña M, García R.

    Stereotactic radiosurgery practice patterns for brain metastases: a survey by the SRS_SBRT_SEOR (Spanish Society of Radiation Oncology) Working Group

    Reports of Practical Oncology and Radiotherapy . 30(4): 513-522.

    [doi:10.5603/rpor.107739]

  • Piredda R, Martínez LGR, Stamatakis K, Martinez-Ortega J, Ferráz AL, Almendral JM, Revilla Y.

    Assessment of molecular modulation by multifrequency electromagnetic pulses to preferably eradicate tumorigenic cells.

    Scientific Reports . 14(1): 30150-30150. Number of citations: 1

    [doi:10.1038/s41598-024-81171-x]

  • González-Lafuente L, Mercado-García E, Vázquez-Sánchez S, González-Moreno D, Boscá L, Fernández-Velasco M, Segura J, Kuro-O M, Ruilope LM, Liaño F, Ruiz-Hurtado G.

    Interleukin-6 as a prognostic marker in acute kidney injury and its klotho-dependent regulation.

    Nefrologia . 44(6): 818-829.

    [doi:10.1016/j.nefroe.2024.11.010]

  • Gonzalez-Lafuente, Laura, Mercado-Garcia, Elisa, Vazquez-Sanchez, Sara, Gonzalez-Moreno, Daniel, Bosca, Lisardo, Fernandez-Velasco, Maria, Segura, Julian, Kuro-O, Makoto, Ruilope, Luis M., Liano, Fernando, Ruiz-Hurtado, Gema.

    Interleukin-6 as a prognostic marker in acute renal injury and its klotho-dependent regulation

    NEFROLOGIA . 44(6): 818-829.

    [doi:10.1016/j.nefro.2024.04.002]

  • Budillon A, Leone A, Passaro E, Silvestro L, Foschini F, Iannelli F, Roca MS, Macchini M, Bruzzese F, Garcia Bermejo ML, Rodriguez Garrote M, Tortora G, Milella M, Reni M, Fuchs C, Hewitt E, Kubiak C, Di Gennaro E, Giannarelli D, Avallone A.

    Randomized phase 2 study of valproic acid combined with simvastatin and gemcitabine/nab-paclitaxel-based regimens in untreated metastatic pancreatic adenocarcinoma patients: the VESPA trial study protocol.

    BMC CANCER . 24(1): 1167-1167. Number of citations: 9

    [doi:10.1186/s12885-024-12936-w]

  • Hernando-Requejo O, Olombrada MVT, Bravo IA, Moreno LA, López-Campos F, Gonzalez ML, Martín MM, Macías VM, de la Pinta C.

    Current landscape of gastrointestinal radiation oncology in Spain: a multicenter real-life survey and comparison with key clinical guidelines.

    Reports of Practical Oncology and Radiotherapy . 29(3): 340-347. Number of citations: 1

    [doi:10.5603/rpor.101096]

  • Nagore D, Candela A, Bürge M, Tamayo E, Murie-Fernández M, Vives M, Monedero P, Álvarez J, Mendez E, Pasqualetto A, Mon T, Pita R, Varela MA, Esteva C, Pereira MA, Sanchez J, Rodriguez MA, Garcia A, Carmona P, López M, Pajares A, Vicente R, Aparicio R, Gragera I, Calderón E, Marcos JM, Gómez L, Rodríguez JM, Matilla A, Medina A, Hernández A, Morales L, Santana L, Garcia E, Montesinos S, Muñoz P, Bravo B, Blanco V.

    Uric acid and acute kidney injury in high-risk patients for developing acute kidney injury undergoing cardiac surgery: A prospective multicenter study.

    Revista espanola de anestesiologia y reanimacion . 71(7): 514-521. Number of citations: 2

    [doi:10.1016/j.redare.2024.04.019]

  • López-Gil JC, García-Silva S, Ruiz-Cañas L, Navarro D, Palencia-Campos A, Giráldez-Trujillo A, Earl J, Dorado J, Gómez-López G, Monfort-Vengut A, Alcalá S, Gaida MM, García-Mulero S, Cabezas-Sáinz P, Batres-Ramos S, Barreto E, Sánchez-Tomero P, Vallespinós M, Ambler L, Lin ML, Aicher A, García García de Paredes A, de la Pinta C, Sanjuanbenito A, Ruz-Caracuel I, Rodríguez-Garrote M, Guerra C, Carrato A, de Cárcer G, Sánchez L, Nombela-Arrieta C, Espinet E, Sanchez-Arevalo Lobo VJ, Heeschen C, Sainz B Jr.

    The Peptidoglycan Recognition Protein 1 confers immune evasive properties on pancreatic cancer stem cells.

    GUT . 73(9): 1489-1508. Number of citations: 15

    [doi:10.1136/gutjnl-2023-330995]

  • Hinojar R, Moreno-Gómez-Toledano R, Conde E, Gonzalez-Gomez A, García-Martin A, González-Portilla P, Fernández-Golfín C, García-Bermejo ML, Zaragoza C, Zamorano JL.

    Circulating miRNA in functional tricuspid regurgitation. Unveiling novel links to heart failure: A pilot study.

    ESC Heart Failure . 11(4): 2272-2286. Number of citations: 4

    [doi:10.1002/ehf2.14765]

  • Meersch M, Weiss R, Strauß C, Albert F, Booke H, Forni L, Pittet JF, Kellum JA, Rosner M, Mehta R, Bellomo R, Rosenberger P, Zarbock A.

    Acute kidney disease beyond day 7 after major surgery: a secondary analysis of the EPIS-AKI trial.

    INTENSIVE CARE MEDICINE . 50(2): 247-257.

    [doi:10.1007/s00134-023-07314-2]

  • Lacalle-Gonzalez C, Florez-Cespedes M, Sanz-Criado L, Ochieng' Otieno M, Ramos-Muñoz E, Fernandez-Aceñero MJ, Ortega-Medina L, Garcia-Foncillas J, Martinez-Useros J.

    DLL3 Is a Prognostic and Potentially Predictive Biomarker for Immunotherapy Linked to PD/PD-L Axis and NOTCH1 in Pancreatic Cancer.

    Biomedicines . 11(10): . Number of citations: 6

    [doi:10.3390/biomedicines11102812]

  • Rincón Ferrari MD, Felipe Correoso MM, Candela Toha Á.

    Assessment of the degree of knowledge of the massive transfusion protocol in four Spanish hospitals.

    MEDICINA CLINICA . 161(7): 312-313. Number of citations: 1

    [doi:10.1016/j.medcli.2023.05.010]

  • Bermejo S, González E, López-Revuelta K, Ibernon M, López D, Martín-Gómez A, Garcia-Osuna R, Linares T, Díaz M, Martín N, Barros X, Marco H, Navarro MI, Esparza N, Elias S, Coloma A, Robles NR, Agraz I, Poch E, Rodas L, Lozano V, Fernández-Fernández B, Hernández E, Martínez MI, Stanescu RI, Moirón JP, García-Fernández N, Goicoechea M, Calero F, Bonet J, Liaño F, Pascual J, Bestard O, Praga M, Fulladosa X, Soler MJ.

    The coexistence of diabetic retinopathy and diabetic nephropathy is associated with worse kidney outcomes.

    Clinical Kidney Journal . 16(10): 1656-1663. Number of citations: 15

    [doi:10.1093/ckj/sfad142]

  • Hernández-González PI, Barquín J, Ortega-Ferrete A, Patón V, Ponce-Alonso M, Romero-Hernández B, Ocaña J, Caminoa A, Conde-Moreno E, Galeano J, Campo RD, García-Pérez JC.

    Anastomotic leak in colorectal cancer surgery: Contribution of gut microbiota and prediction approaches.

    Colorectal Disease . 25: 2187-2197. Number of citations: 11

    [doi:10.1111/codi.16733]

  • Poveda J, González-Lafuente L, Vázquez-Sánchez S, Mercado-García E, Rodríguez-Sánchez E, García-Consuegra I, Sanz AB, Segura J, Fernández-Velasco M, Liaño F, Ruilope LM, Ruiz-Hurtado G.

    Targeting the TWEAK-Fn14 pathway prevents dysfunction in cardiac calcium handling after acute kidney injury.

    JOURNAL OF PATHOLOGY . 261: 427-441. Number of citations: 7

    [doi:10.1002/path.6200]

  • Urbanova M, Cihova M, Buocikova V, Slopovsky J, Dubovan P, Pindak D, Tomas M, García-Bermejo L, Rodríguez-Garrote M, Earl J, Kohl Y, Kataki A, Dusinska M, Sainz B Jr, Smolkova B, Gabelova A.

    Nanomedicine and epigenetics: New alliances to increase the odds in pancreatic cancer survival.

    BIOMEDICINE & PHARMACOTHERAPY . 165: 115179-115179. Number of citations: 16

    [doi:10.1016/j.biopha.2023.115179]