Biomarkers and therapeutics targets

2022 ACTIVITY INDICATORS

  • 2 European projects: H2020- EATRIS-Plus and HE-REMEDI4ALL
  • 5 competitive projects led by: ISCIII, CAM and MICINN
  • 2 intramural projects FIBioHRC
  • 2 private competitive innovation projects led by: ISCIII, CAM and MICINN 
  • 1 clinical study led
  • 2 competitive HR contracts: CAM and MICINN
  • 13 publications
  • IF: 106,48
  • Q1 publications: 8 (62%)
  • D1 publications: 3(23%)
  • 2 supervised doctoral theses read
  • 2 awards / recognitions: professional career award (Diputación de Guadalajara) and second prize in I Jornada de Investigación de Estudiantes de Doctorado (JOINED IRYCIS 2022, FIBioHRC).
  • Project Evaluator: 1 IP
  • Member of Editorial Committee: 1 PI
  • 4 patent families: 
    • 2 extended internationally in 10 countries. Both protect microRNAs useful in the early diagnosis and predisposition of Acute Renal Failure (PCT/ES2012/070858 and PCT/ES2010/070579).
    • 1 international patent application (USA and Europe) protecting miR127 as a new therapeutic target in Chronic Kidney Disease European Application16382399.0
    • 1 European patent application: EP22383047.2 protecting microRNAs in colorectal cancer.
  • 1 host visitor and 6 months stay:
    • Istituto Nazionale Tumori- IRCCS G. Pascale (Italy)

Milestones

  1. Expansion of the group's transfer activity: i) consolidation of the collaboration with AM-PHARMA for the validation of patented miRNAs as biomarkers of response of a new drug for kidney damage; ii) start of collaboration with AMADIX, through the RETOS-Colaboración 2022 project.
  2. Consolidation of the Personalised Medicine research line in colo-rectal cancer and new PI in the group, Dr Elisa Conde, due to the achievement of the DTS project: miRNaMut Platform. Consolidation of collaboration with Dr Carolina de la Pinta, Radiation Oncology, increasing the multidisciplinary nature of the group.
  3. Generation of new intellectual property regarding the potential of miR326 as a new therapeutic target in colorectal cancer, by means of a European patent application, in collaboration with the Immunology Department.
  4. Consolidation of the group's participation and relevance in national and international platforms and infrastructures: 1) EATRIS: new REDEMI4all project for drug repositioning in pancreatic cancer, consolidation of Dr García Bermejo as co-chair of the Biomarkers Platform and her new position as Scientific Director of the EATRIS Spain Node; 2) AMRI: European Alliance of EATRIS, BBMRI and ECRIN. BBMRI includes the National Platform for Biobanks and Biomodels; ECRIN includes the National Platform for Clinical Trials SCReen.
  5. Consolidation of the group's participation in national and international cooperative research structures in Renal Diseases: RICOR2040, CAM Biomedicine Groups and Consortium for European projects ERANET- RD-JPI, in rare renal diseases.

Bibliometrics

  Articles Accum. FI Mean FI Articles Q1 or Q2 % in Q1 or Q2 Articles D1 % in D1
2018 8 28,97 4,83 4 50 1 13
2019 11 54,90 9,15 8 73 3 27
2020 14 77,19 12,87 11 79 4 29
2021 18 93,99 15,67 14 78 3 17
2022 13 106,48 8,19 12 92 3 23
  64 361,53 10,14 49 77 14 22

* Only original articles, editorials, guidelines and reviews

Networks and alliances