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Lung cancer translational research

The Lung Cancer Translational Research Group (GITCaP) is dedicated to the research and treatment of thoracic tumors, with a multidisciplinary team of oncologists, surgeons, pathologists, radiologists, pulmonologists and other specialists. Their lines of research focus on identifying predictive markers of treatment efficacy and improving patient survival and quality of life. In addition, they collaborate in clinical trials and projects on microbiota, blood biomarkers, cancer in non-smokers and the impact of radon. They also investigate the use of artificial intelligence in radiology and the promotion of physical exercise to reduce inflammation.

Search for publications

Only original articles, editorials, guidelines.

  • Solomon BJ, Tan DSW, de Castro G Jr, Cobo M, Garassino MC, Zhang J, Johnson BE, Lee JM, Garrido P, Butler AA, Pelletier MR, Savchenko A, Ji L, Brase JC, Caparica R, Demanse D, Wu J, Bossen C, Mok T.

    The Impact of the Tumor Microenvironment on the Effect of IL-1ß Blockade in NSCLC: Biomarker Analyses from CANOPY-1 and CANOPY-N Trials

    Cancer Research Communications . 5(4): 632-646. Number of citations: 1

    [doi:10.1158/2767-9764.CRC-24-0490]

  • García-Pardo M, García de Herreros M, Auclin E, Ferriol-Galmes M, Laguna JC, Gorría T, Caravaca G, Sart J, Albarrán-Artahona V, López-Castro R, Teixidó C, Castellano G, Martínez Bedmar A, Arcocha A, Alcolea L, Jiménez M, Bernabeu M, Delgado-Cano D, Navarro A, Prat A, Reguart N, Elio J, Garrido P, Leighl NB, Besse B, Mezquita L.

    Frequency of driver oncogenic alterations in NSCLC and estimated indoor radon exposure in Europe (RADON EUROPE study)

    THERAPEUTIC ADVANCES IN MEDICAL ONCOLOGY . 17: .

    [doi:10.1177/17588359251351449]

  • Salgado-Parente A, deVicente AG, Alarcón-Rodríguez J, Rivero Jiménez N.

    Cervical aortic arch: a rare congenital anomaly.

    Anales De Pediatria . 102(1): 503697-503697.

    [doi:10.1016/j.anpede.2024.503697]

  • Cortés-Salgado A, Serrano JJ, Cordero Pereda D, Menacho M, del Rey JM, Del Campo-Albendea L, Saavedra C, Chamorro J, Rosero D, Sotoca P, Guillén-Ponce C, Guerra E, Fernández-Abad M, López-Miranda E, Martínez-Jáñez N, Gion M, Salazar MT, Agudo-Quílez P, Garrido P, Alonso Salinas GL.

    Anthracyclines-induced cardiotoxicity in patients with early breast cancer carrying germline BRCA1/2 mutation: the BRCAN study.

    ONCOLOGIST . : .

    [doi:10.1093/oncolo/oyae299]

  • Villanueva Campos A, Canales Lachén E, Suevos Ballesteros C, Alarcón Rodríguez J.

    Multi-energy CT and iodinated contrast.

    Radiologia . 66 Suppl 2: .

    [doi:10.1016/j.rxeng.2024.03.011]

  • Planchard D, Wolf J, Solomon B, Sebastian M, Wermke M, Heist RS, Sun JM, Min Kim T, Reguart N, Sanmamed MF, Felip E, Garrido P, Santoro A, Bootle D, Couillebault XM, Gaur A, Mueller C, Poggio T, Yang J, Moschetta M, Dooms C.

    A phase Ib study of the combination of naporafenib with rineterkib or trametinib in patients with advanced and metastatic KRAS- or BRAF-mutant non-small cell lung cancer.

    Lung Cancer . 197: 107964-107964.

    [doi:10.1016/j.lungcan.2024.107964]

  • Santoro A, Pilar G, Tan DSW, Zugazagoitia J, Shepherd FA, Bearz A, Barlesi F, Kim TM, Overbeck TR, Felip E, Cai C, Eddy S, McCulloch T, Schaefer ES.

    Spartalizumab in combination with platinum-doublet chemotherapy with or without canakinumab in patients with PD-L1-unselected, metastatic NSCLC.

    Bmc Cancer . 24(1): 1307-1307.

    [doi:10.1186/s12885-024-12841-2]

  • Isla D, Álvarez R, Arnal M, Arriola E, Azkarate A, Azkona E, García-Campelo R, Garrido P, Nadal E, Ortega AL, Carcedo D, Crespo M, Lavara J, Córcoles F, Bernabé R.

    Detection of genomic alterations in liquid biopsies from patients with non-small cell lung cancer using FoundationOne Liquid CDx: a cost-effectiveness analysis.

    Journal of medical economics . 27(1): 1379-1387.

    [doi:10.1080/13696998.2024.2413289]

  • Carretero-Barrio I, Pijuan L, Illarramendi A, Curto D, López-Ríos F, Estébanez-Gallo Á, Castellvi J, Granados-Aparici S, Compañ-Quilis D, Noguera R, Esteban-Rodríguez I, Sánchez-Güerri I, Ramos-Guerra AD, Ortuño JE, Garrido P, Ledesma-Carbayo MJ, Benito A, Palacios J.

    Concordance in the estimation of tumor percentage in non-small cell lung cancer using digital pathology.

    SCIENTIFIC REPORTS . 14(1): 24163-24163.

    [doi:10.1038/s41598-024-75175-w]

  • Gorospe, Luis, Mirambeaux-Villalona, Rosa Mariela, Arrieta, Paola.

    A tiny green lesion mimicking a big problem.

    EUROPEAN JOURNAL OF INTERNAL MEDICINE . 130: 153-154.

    [doi:10.1016/j.ejim.2024.10.009]

  • Dowlati A, Hummel HD, Champiat S, Olmedo ME, Boyer M, He K, Steeghs N, Izumi H, Johnson ML, Yoshida T, Bouchaab H, Borghaei H, Felip E, Jost PJ, Gadgeel S, Chen X, Yu Y, Martinez P, Parkes A, Paz-Ares L.

    Sustained Clinical Benefit and Intracranial Activity of Tarlatamab in Previously Treated Small Cell Lung Cancer: DeLLphi-300 Trial Update.

    JOURNAL OF CLINICAL ONCOLOGY . 42(29): 3392-3399. Number of citations: 1

    [doi:10.1200/JCO.24.00553]

  • Schmid S, Garcia M, Zhan L, Cheng S, Khan K, Chowdhury M, Sabouhanian A, Herman J, Walia P, Strom E, Brown MC, Patel D, Xu W, Shepherd FA, Sacher AG, Leighl NB, Bradbury PA, Liu G, Shultz D.

    Outcomes with non-small cell lung cancer and brain-only metastasis.

    Heliyon . 10(17): .

    [doi:10.1016/j.heliyon.2024.e37082]

  • Gorospe L, Reguero-Callejas ME, Donate-Velasco I.

    Inflammatory Myofibroblastic Tumor of the Pleura With Lung Metastases in an Elderly Patient.

    ARCHIVOS DE BRONCONEUMOLOGIA . : .

    [doi:10.1016/j.arbres.2024.07.024]

  • Albarrán V, Guerrero P, de Quevedo CG, González C, Chamorro J, Rosero DI, Moreno J, Calvo JC, de Aguado PP, Alía V, Sotoca P, Barrill AM, Román MS, Álvarez-Ballesteros P, Serrano JJ, Soria A, Olmedo ME, Saavedra C, Cortés A, Gómez A, Lage Y, Ruiz Á, Ferreiro MR, Longo F, Garrido P, Gajate P.

    Negative association of steroids with immunotherapy efficacy in a multi-tumor cohort: time and dose-dependent.

    CANCER IMMUNOLOGY IMMUNOTHERAPY . 73(10): 186-186. Number of citations: 2

    [doi:10.1007/s00262-024-03772-9]

  • Fra S, Caballero-Silva U, Cabañero-Sánchez A, Muñoz-Molina GM, Cavestany García-Matres C, Lozano-Ayala JD, Lomanto-Navarro L, Vílchez-Pernias E, Moreno-Mata N.

    Implementation of the Versius robotic surgical system for thoracic surgery: first clinical evaluation of feasibility and performance.

    EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY . 66(2): . Number of citations: 1

    [doi:10.1093/ejcts/ezae286]

  • Fuentes-Martín Á, Martínez-Hernández NJ, Cabañero Sánchez A, Figueroa Almánzar S, Call S, Bolufer S, Gómez de Antonio D, Muñoz Moreno MF, Embun R, Cilleruelo Ramos Á.

    Impact of radiological follow-up frequency on resected lung cancer: a propensity score matching analysis.

    JOURNAL OF THORACIC DISEASE . 16(7): 4275-4285.

    [doi:10.21037/jtd-23-1973]

  • Ventura-Díaz S, González-Huete A, Gómez-Bermejo MA, Antolinos-Macho E, Alarcón-Rodríguez J, Gorospe-Sarasúa L.

    Imaging findings of the postoperative chest: What the radiologist should know.

    Radiologia . 66(4): 353-365.

    [doi:10.1016/j.rxeng.2023.05.009]

  • Caballero-Silva U, Fra-Fernández S, Cavestany García-Matres CR, Cabañero-Sánchez A, Moreno-Mata N.

    Results of the implementation of a specialized cervical tracheal surgery program.

    Cirugia Espanola . 102(11): 617-619.

    [doi:10.1016/j.cireng.2024.05.014]