Rheumatology

The group focuses its research projects on non-traumatic musculoskeletal diseases, mainly autoimmune diseases (Lupus, Scleroderma, Vasculitis, Inflammatory myopathies,...), and immune-mediated arthropathies (rheumatoid arthritis, psoriatic arthritis, spondyloarthritis,...). The group has mainly carried out clinical research studies (description of disease phenotypes, response to treatments) and, in recent years, basic research (histopathology, immunology, and genetics) has been added. Likewise, innovative projects have been developed (training of rheumatic patients, thermal imaging in arthritis, mobile devices for monitoring chronic diseases) for application to clinical practice. Four members of the group are doctors and 5 more are finishing their PhD. We have got updated records of disease groups, clinical situation and prescribed advanced (biological) treatments. We have got a collection of biological samples of all these autoimmune diseases in different stages of evolution and different treatments

2025 ACTIVITY INDICATORS

  • 1 competitive national public project: F. Madrid+D
  • 8 private projects led
  • 45 clinical studies
  • 30 publications
  • IF: 102.60
  • Publications in Q1: 16 (53%)
  • Publications in D1: 12 (40%)
  • Evaluators in medical agencies and societies: 1 researcher

Milestones

  1. The IMIDs project, "Implementation of a Comprehensive Care Model for Patients with Immune-Mediated Diseases," begins, through a multidisciplinary coordination and management unit, coordinated by the group to improve hospital care for patients with various immune-mediated diseases.
  2. Participation in the first clinical trial to demonstrate the safety and efficacy of CAR-T cell therapy in patients with difficult-to-treat rheumatoid arthritis and severe refractory Sjögren's disease with organ involvement.
  3. The BIOHOPES project, coordinated by the group, is launched to detect cellular biomarkers to predict the response to methotrexate in patients with rheumatoid arthritis.
  4. A lupus preceptorship is organized with the participation of professionals in nephrology, dermatology, and nursing. Twenty students from around the world learn the advanced clinical management of this disease over two days.
  5. The 10th Conference on Systemic Autoimmune Diseases and the 8th Conference on Autoinflammatory Diseases are held at CAM-Hospital Ramón y Cajal.

Networks and alliances