Neuroproteins-stroke

Group leader

Alberto Alcázar González

alberto.alcazar(ELIMINAR)@hrc.es

Principal Investigator

  • Jaime Masjuán Vallejo

Collaborators

  • Alicia de Felipe Mimbrera
  • Mercedes Gómez-Calcerrada Iniesta
  • Emma Martínez Alonso
  • Ignacio Regidor Bailly-Bailliere
  • María Consuelo Matute Lozano
  • Rocío Vera Lechuga
  • Antonio Cruz Culebras
  • José María Solís Torralba
  • Jesús Miguel Hernández Guijo
  • José Victoriano Barbado Fernández
  • Alejandro Escobar Peso
  • Iris Álvarez Merz
  • Lorena Peracho Benito
Imagen equipo

Group leader

Alberto Alcázar González

alberto.alcazar(ELIMINAR)@hrc.es

Principal Investigator

  • Jaime Masjuán Vallejo

Collaborators

  • Alicia de Felipe Mimbrera
  • Mercedes Gómez-Calcerrada Iniesta
  • Emma Martínez Alonso
  • Ignacio Regidor Bailly-Bailliere
  • María Consuelo Matute Lozano
  • Rocío Vera Lechuga
  • Antonio Cruz Culebras
  • José María Solís Torralba
  • Jesús Miguel Hernández Guijo
  • José Victoriano Barbado Fernández
  • Alejandro Escobar Peso
  • Iris Álvarez Merz
  • Lorena Peracho Benito

Strategic objectives

  • Advance in the understanding of cerebral ischemia pathology.
  • Development of pharmacological strategies with therapeutic potential to improve functional recovery after ischemic stroke.
  • Treatment of strokes in the acute phase.

Research lines
Lines of clinical research:

  • Secondary stroke prevention with direct action anticoagulants.
  • Endovascular treatment of cerebral infarction.
  • Cerebrovascular complications of patients under treatment with antivitamins K.
  • Cerebral infarctions in patients on a flight.
  • Quantitative analysis of thrombus extraction with mechanical thrombectomy.

Lines of experimental research:

  • Mechanisms of death and neuroprotection in cerebral ischemia.
  • Identification of proteins involved in neurorepair after cerebral ischemia. Clinical experimental study.
  • Exploration of new neuroprotective drugs for cerebral ischemia.
  • Study of non-excitatory amino acid transporters as new molecular targets in brain damage caused by ischemia.

Location

Stroke Unit

Neurology Service, 5D


Neuroproteins and Ischemia Laboratory & Proteomics Laboratory

Dept. Research -1D

Ramón y Cajal University Hospital

Keywords

stroke, neuroprotection, brain ischemia, experimental models, therapeutic targets, reperfusion treatments, drug trial, molecular mechanisms, neuronal death.