Photobiology and Bioelectromagnetism


Mª Luisa Hernández Bule


María Antonia Martínez Pascual

Elena Toledano Macías

Rosa Cristina Jara Laguna

Luis Alfonso Pérez González


  • Noteworthy

    Group with extensive experience in the study of the interaction of living beings with non-ionizing radiation. One of the research lines of the group is the study of the molecular basis of physical therapies based on the use of RF and ELF electromagnetic radiation. Currently, the study of radiation in the visible light and ultraviolet range is another of the lines of research of the Photobiology and Bioelectromagnetism Unit, and in this sense, projects related to photoprotection, photobiomodulation and phototherapy are being developed.


    • Toledano-Macías E, Martínez-Pascual MA, Hernández-Bule ML. Corrientes eléctricas de 448?kHz regulan vías anti-senescencia en fibroblastos dérmicos humanos. J Cosmet Dermatol. 2023 Nov. doi: 10.1111/jocd.16019.
    • Fernández-Guarino M, Hernández-Bule ML, Bacci S. Procesos celulares y moleculares en la cicatrización de heridas. Biomedicines. 2023 Sep 13;11(9):2526. doi: 10.3390/biomedicines11092526.
    • Hernández-Bule ML, Toledano-Macías E, Pérez-González LA, Martínez-Pascual MA, Fernández-Guarino M. Anti-Fibrotic Effects of RF Electric Currents. Int J Mol Sci. 2023 Jul 1;24(13).
    • Fernández-Guarino M, Hernández-Bule ML, Bacci S. Cells and Processes in Wound Healing: Avances más recientes. 2023 May. doi: 10.20944/preprints202305.0643.v1
    • Fernández-Guarino M, Bacci S, Pérez González LA, Bermejo-Martínez M, Cecilia-Matilla A, Hernández-Bule ML. Papel de las terapias físicas en la cicatrización de heridas y cicatrización asistida. Int J Mol Sci. 2023 abr 19;24(8):7487. doi: 10.3390/ijms24087487.
    • Hernández-Bule ML, Toledano-Macías E, Martínez MA et al. Effects of RF Currents on Cytokines Production in Human Keratinocytes. 2023 Marzo. .doi: 10.3390/ECB2023-14096.
  • Equipment

    For Bioelectromagnetism tests:

    • Stimulators - signal generators in the range of extremely low frequencies (ELF) to radio frequencies (RF).
    • Helmholtz coils for in vitro study of magnetic fields.
    • CO2 incubators for in vitro exposure, equipped with shielding chamber against ELF electromagnetic environmental contamination.
    • Exposure systems for in vitro RF stimulation.
    • EMDEX II personal dosimeters for frequency fields between 40 Hz and 0.8 GHz.
    • Laboratories equipped to evaluate cellular and molecular response to radiation exposure in the ELF - RF range.
    • Anechoic chamber for rodent exposure to radiofrequencies up to 10 GHz, located in the animal house.

    For Photobiology assays:

    • Exposure systems for in vitro stimulation with wavelengths in the visible spectrum (blue: 448 nm; green: 530 nm; red: 655 nm) and ultraviolet (UVA: 365 nm and UVB: 312 nm).
      Laboratories equipped for exposure and assessment of cellular and molecular response to radiation in the range between visible and UV light.
      Laboratories equipped for the assessment of cellular and molecular response to exposure to radiation in the ELF - RF range.
      Radiometers for infrared, visible light and ultraviolet wavelengths (between 260 nm and 1100 nm).
  • Service portfolio and prices

    **Consult fees with the unit

    • Characterization of in vivo and in vitro biological responses to electric fields and currents, ELF magnetic fields, non-ionizing radiation (ELF-RF), radiation in the visible spectrum and ultraviolet radiation.
    • In vivo research studies to RF stimuli: use of anechoic chamber. Use of ELF, RF, ultraviolet radiation and visible light exposure systems for in vitro systems.
    • Dosimetry of electromagnetic fields in the ELF - RF range. Infrared, visible and ultraviolet light radiometry. Transmitted light quantification tests.
    • Advice on photoprotection in the workplace and environment. Consultancy on safety and protection against NIR.