Neurodegenerative diseases: therapy development

2022 Activity indicators

7 competitive projects led- ISCIII, MICINN, CAM.
3 private led projects.
11 competitive HR contracts.
5 publications.
IF: 27.33
Publications in Q1: 2 (40 %).
4 awards: UCM & Spanish Society for Research on Cannabinoids
Project and scientific career evaluators at 5 national agencies and European universities: 3 PIs.
Members of editorial committees: 2 PI and 4 collaborators
10 visitors received and +44 months' stay:
- University of Antioquia in Medellin (Colombia)
- Centro Educativo FP Corredor del Henares
- Centro Educativo Escuela Técnica de Enseñanzas Especializadas
- Universidad Complutense de Madrid

Milestones

Alonso C, Satta V, Díez-Gutiérrez P, Fernández-Ruiz J, Sagredo O. Investigación preclínica del β-cariofileno como agente terapéutico en un modelo murino experimental del síndrome de Dravet. Neurofarmacología. 2022; 205:108914. doi: 10.1016/j.neuropharm.2021.108914. PMID: 34875285.
Lastres-Becker I, de Lago E, Martínez A, Fernández-Ruiz J. New Statement about NRF2 in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Biomoléculas. 2022; 12(9):1200. doi: 10.3390/biom12091200. PMID: 36139039
Maestro I, de la Ballina LR, Porras G, Corrochano S, De Lago E, Simonsen A, Boya P, Martínez A. Descubrimiento de inhibidores de mitofagia con potencial terapéutico en diferentes mutaciones de esclerosis lateral amiotrófica familiar. Int J Mol Sci. 2022; 23(20):12676. doi: 10.3390/ijms232012676. PMID: 36293534.
Nozal V, Martínez-González L, Gomez-Almeria M, Gonzalo-Consuegra C, Santana P, Chaikuad A, Pérez-Cuevas E, Knapp S, Lietha D, Ramírez D, Petralla S, Monti B, Gil C, Martín-Requero A, Palomo V, de Lago E, Martinez A. TDP-43 Modulation by Tau-Tubulin Kinase 1 Inhibitors: Una Nueva Vía para la Futura Terapia de la Esclerosis Lateral Amiotrófica. J Med Chem. 2022; 65(2):1585-1607. doi: 10.1021/acs.jmedchem.1c01942. PMID: 34978799.
Riboldi GM, Vialle RA, Navarro E, Udine E, de Paiva Lopes K, Humphrey J, Allan A, Parks M, Henderson B, Astudillo K, Argyrou C, Zhuang M, Sikder T, Oriol Narcis J, Kumar SD, Janssen W, Sowa A, Comi GP, Di Fonzo A, Crary JF, Frucht SJ, Raj T. Transcriptome deregulation of peripheral monocytes and whole blood in GBA-related Parkinson's disease. Mol Neurodegener. 2022; 17(1):52. doi: 10.1186/s13024-022-00554-8. PMID: 35978378.

Bibliometrics

	Articles	ACCUM. FI	MEAN IF	ARTICLES Q1 OR Q2	% IN Q1 OR Q2	ARTICLES D1	% IN D1
2018	11	52,68	4,79	11	100	3	27
2019	7	31,86	4,55	7	100	2	29
2020	6	29,85	4,98	6	100	1	17
2021	12	74,50	6,21	12	100	3	25
2022	5	27,33	5,47	5	100	0	0
	41	216,22	5,20	41	100	9	22