Milestones

1. Consensus document led by the group: "Llàcer P, Romero G, Trullàs JC, de la Espriella R, Cobo M, Quiroga B, Casado J, Slon MF, Morales JL, Morgado JI, Ortiz A, Formiga F, Melendo M, de Sequera P, Recio A, Díez J, Manzano L, Núñez J. Consensus on the approach to hydrosaline overload in acute heart failure. SEMI/SEC/S.E.N. Rev Esp Cardiol (Engl Ed).
2. Led clinical practice guide: González A, Del Arco C, Lucas D, Frías M, Guillán M, Méndez M, Ruiz M, Aguado AC, Fraile J, Latorre G, Castañeda S. Executive summary on the optimization of the multidisciplinary and integrated approach to polymyalgia rheumatica and giant cell arteritis in the Madrid region. Rev Clin Esp (Barc). 2023;224(1): 48 - 56. DOI:10.1016/j.rceng.2023.12.009.
3. Inclusion of the results of the independent multicenter clinical trial CLOROTIC (NCT01647932) led by the group in the main international guidelines and consensus documents on heart failure: European Society of Cardiology (ESC) 2023 [PMID: 37622666], American College of Cardiology 2023 [PMID: 37137593] and 2024 [PMID: 39127954], Heart Failure Association - ESC [PMID: 37208936], and European Federation of Internal Medicine [PMID: 38453571].
4. High impact publication of the results of the independent clinical trial COLICA (ICI19/00055): "Pascual D, Núñez J, Pérez MT, González JR, Taibo M, Llàcer P, Delgado J, Villar S, Mirabet S, Aimo A, Riquelme A, Anguita M, Martínez M, Noguera JA, Ibáñez B, Bayés A, COLICA I. Colchicine in acutely decompensated heart failure: the COLICA trial. Eur Heart J. 2024;45(45): 4826 - 4836. DOI:10.1093/eurheartj/ehae538.
5. Featured original article: López L, Vázquez ME, Colón C, Bravo SB, Barbosa S, Álvarez JV, Sánchez R, López M, López M, Villacorta E, Goicoechea MA, Guerrero FJ, Ortolano S, Leao E, Hermida Á, Couce ML. Characterization of the plasma proteomic profi le of Fabry disease: Potential sex- and clinical phenotype-specific biomarkers. TRANSL RES. 2024;269: 47 - 63. DOI:10.1016/j. trsl.2024.02.006.