Milestones

1. Description of a new ABCA1 variant associated with impaired platelet production that contributes to thrombocytopenia in a family with Tangier disease (severe HDL deficiency) (doi: 10.1016/j.jacl.2025.12.009).
2. Fernández C, Olmos S, Sánchez L, Terrados S, Diéguez MDC, Fernández M, Vlaicu C, Cerecedo I, Gonzalo A, de la Hoz B, Martínez-Botas J. Predicting Tolerance to Cow's Milk Allergy in Children Using IgE and IgG4 Peptide Binding Profiles. Cells. 2025;14(5): 344. DOI:10.3390/cells14050344. Identification of IgE and IgG4 peptide biomarkers capable of predicting the development of tolerance to cow's milk in children with allergy, providing a promising tool for clinical prognosis and early patient stratification.
3. de Nicolás B, Fernández C, Gutierrez P, Ballester A, Rodriguez N, Martínez-Botas J, de la Hoz B, Andres A, Solano E, Gomez ME, Diaz LG, Arrebola DM, Stewart VL, García E, Azcarraga C, Berna E, Ortega S, Fernández M. Lymphocyte Transformation Tests and Patch Tests to Identify Drugs Potentially Associated With Bullous Pemphigoid Development. Int. J. Dermatol. 2025;64(9): 1636-1643. DOI:10.1111/ijd.17849. Use of the Lymphocyte Transformation Test (LTT) as a Key Tool for Identifying Drugs That Trigger Bullous Pemphigoid.
4. Torrecilla M, Pardo V, Fuentes AC, G-García ME, Fernández M, López JL, Puigdueta C, Zamora C, Pérez A, Aranda JF, Busto R, Gahete MD, Luque RM, Ramírez CM. MiR-7 inhibits the progression of glioblastoma by impairing autophagy resolution, energy metabolism, and ECM remodeling. J. Exp. Clin. Cancer Res. 2025;44(1): 237-237. DOI:10.1186/s13046-025-03504-6. MiR-7 inhibits the progression of glioblastoma by altering autophagy resolution, energy metabolism, and extracellular matrix remodeling.
5. Organization of the 4th International Lipidomics Society Conference. Madrid, Oct. 28-31, 2025. Ramón y Cajal University Hospital - IRYCIS (https://ilsconf2025madrid.com/).