Renal and vascular physiology and phisiopathology

Group leader

Diego María Rodríguez Puyol

Principal Investigators

  • Manuel Rodriguez Puyol
  • Susana López Ongil
  • María Piedad Ruiz Torres
  • Laura Calleros Basilio

Collaborators

  • Gema Olmos Centenera
  • Sergio de Frutos García
  • José Manuel Gómez Pulido
  • Daniel Rodríguez García
  • Jose Luis Castillo Sequera
  • María Luz Polo Luque
Imagen equipo

Group leader

Diego María Rodríguez Puyol

Principal Investigators

  • Manuel Rodriguez Puyol
  • Susana López Ongil
  • María Piedad Ruiz Torres
  • Laura Calleros Basilio

Collaborators

  • Gema Olmos Centenera
  • Sergio de Frutos García
  • José Manuel Gómez Pulido
  • Daniel Rodríguez García
  • Jose Luis Castillo Sequera
  • María Luz Polo Luque

Strategic objectives

  • Maintain four active research projects from the National Plan.
  • Achieve six publications in the first quartile from our area of knowledge in the next 2 years.
  • Endorse at least two reliably active collaborations with other members of IRYCIS or Ramón y Cajal Hospital (supported in joint projects, joint publications or joint lines of development).
  • Give an annual scientific talk for the entire institute (with a prior invitation)
  • Facilitate the cooperation of other members of IRYCIS in at least one annual teaching activity of Alcalá University.
  • Maintain regular collaboration with at least 1 private company

Research lines

  • Integrin-linked kinase: a possible biomarker of progression of chronic renal disease (CRD) and modulator of the monocyte dysfunction responsible for cardiovascular damage
  • Integrin-linked kinase: its role in the progression of insulin resistance and the development of obesity.
  • Importance of phosphorous in the development of vascular alterations in the elderly and patients with arteriosclerosis. New approaches for the evaluation of the problem.
  • Importance of phosphorous in the development of sarcopenia in the elderly and patients with chronic renal disease. New approaches for the evaluation of the problem.
  • Mass data analysis in the prevention of hemodialysis-associated complications.

Location

 Faculty of Medicine


 Alcalá University
 +34 91 887 81 00 (ext. 2562)

 Link to UAH group

Keywords

Chronic renal disease, extracellular matrix, integrin-linked kinase, GLUT4, AQP2, endothelial dysfunction, phosphorous, sarcopenia, cellular senescence, haemodialysis.