Renal and vascular physiology and phisiopathology

Group leader

Diego María Rodríguez Puyol

Principal Investigator

  • María Piedad Ruiz Torres
  • Laura Calleros Basilio
  • José Manuel Gómez Pulido

Collaborating Staff

  • Gema Olmos Centenera
  • Sergio de Frutos García
  • Jose Luis Castillo Sequera
  • María Luz Polo Luque
  • Ariadna Moreno Piedra
  • Francisco Javier Bueno Guillén
  • Alberto Garcés Jiménez
  • Juan Antonio Gómez Pulido
  • Sergio García Villoria
  • Alba Silvestre Vargas
  • Elena Alcalde Estévez
  • Belen Molina Martinez
Imagen equipo

Group leader

Diego María Rodríguez Puyol

Principal Investigator

  • María Piedad Ruiz Torres
  • Laura Calleros Basilio
  • José Manuel Gómez Pulido

Collaborating Staff

  • Gema Olmos Centenera
  • Sergio de Frutos García
  • Jose Luis Castillo Sequera
  • María Luz Polo Luque
  • Ariadna Moreno Piedra
  • Francisco Javier Bueno Guillén
  • Alberto Garcés Jiménez
  • Juan Antonio Gómez Pulido
  • Sergio García Villoria
  • Alba Silvestre Vargas
  • Elena Alcalde Estévez
  • Belen Molina Martinez

Strategic objectives

  • Four active research projects from the National Plan.
  • Six publications in the first quartile of their area of expertise.
  • Two demonstrably active collaborations with other members of IRYCIS or the Ramón y Cajal University Hospital (supported by joint projects, publications, and/or lines of development).
  • At least one annual scientific talk for the entire Institute (by invitation).
  • Facilitate the collaboration of other IRYCIS members in at least one annual teaching activity at the University of Alcalá.
  • Regular collaboration with at least one private company.

Research lines

  • Integrin-linked kinase: a potential biomarker of chronic kidney disease (CKD) progression and a modulator of monocyte dysfunction responsible for cardiovascular damage.
  • Integrin-linked kinase: a role in the progression of insulin resistance and the development of obesity.
  • Importance of phosphorus in the genesis of vascular disorders in the elderly and patients with arteriosclerosis. New approaches to assessing the problem.
  • Importance of phosphorus in the genesis of sarcopenia in the elderly and patients with chronic kidney disease. New approaches to assessing the problem.
  • Massive data analysis in the prevention of complications associated with hemodialysis.

Location

Faculty of Medicine 

Alcalá University

+34 91 887 81 00 (ext. 2562)

 Link to UAH group

Keywords

chronic kidney disease, extracellular matrix, integrin-linked kinase, GLUT4, AQP2, endothelial dysfunction, phosphorus, sarcopenia, cellular senescence, hemodialysis