Multiple Sclerosis

Group leader

Luisa María Villar Guimerans

luisamaria.villar(ELIMINAR)@salud.madrid.org

Tlf.: 0034 913368029

Principal Investigator

  • Eulalia Rodríguez Martín

Collaborators

  • María Mercedes Espiño Martínez
  • Ernesto Roldán Santiago
  • Lucienne Costa-Frossard França
  • Susana Sainz de la Maza Cantero
  • Amalia Tejeda Velarde
  • Enrique Monreal Laguillo
  • José Ignacio Fernández Velasco
  • Noelia Villarrubia Migallón
  • Paulette Esperanza Walo Delgado
Imagen equipo

Group leader

Luisa María Villar Guimerans

luisamaria.villar(ELIMINAR)@salud.madrid.org

Tlf.: 0034 913368029

Principal Investigator

  • Eulalia Rodríguez Martín

Collaborators

  • María Mercedes Espiño Martínez
  • Ernesto Roldán Santiago
  • Lucienne Costa-Frossard França
  • Susana Sainz de la Maza Cantero
  • Amalia Tejeda Velarde
  • Enrique Monreal Laguillo
  • José Ignacio Fernández Velasco
  • Noelia Villarrubia Migallón
  • Paulette Esperanza Walo Delgado

Strategic Objectives

Our objective is to explore the physiopathological mechanisms of MS, with the aim to identify new therapeutic targets of the disease and contribute to personalised patient treatment.

One of our strategic objectives is the study of the mechanisms associated with the changes that occur in patients with age and the progressive form of the disease, for which there are currently no approved modifying treatments. This is particularly relevant, since age usually brings a lack of gradual response to many of the currently approved MS therapies.

Research Lines

  • The association of gut microbiota with the course of MS
  • Search for biomarkers that identify good responders to different biological therapies in MS
  • Search for biomarkers that identify the different forms of MS
  • Immunological mechanisms that are associated with the progressive forms of MS
  • Immunological mechanisms that are associated with intrathecal IgM synthesis in MS
  • Mechanisms that are associated with age-related worsening in MS

Location

Laboratory:

Immunology Service. 1st floor left..

Clinical Unit:

Neurology Service: 2nd floor right.          
Ramón y Cajal University Hospital

Keywords

multiple sclerosis, biomarkers, immunological mechanisms, B cells, antibodies.