Enfermedades neurodegenerativas: mecanismos patogénicos

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Sólo se han incluido artículos originales, editoriales y revisiones.

  • Yan Y, Serra V, Prudkin L, Scaltriti M, Murli S, Rodríguez O, Guzman M, Sampath D, Nannini M, Xiao Y, Wagle MC, Wu JQ, Wongchenko M, Hampton G, Ramakrishnan V, Lackner MR, Saura C, Roda D, Cervantes A, Tabernero J, Patel P, Baselga J.

    Evaluation and Clinical Analyses of Downstream Targets of the Akt Inhibitor GDC-0068

    CLINICAL CANCER RESEARCH . 19(24): 6976-6986. Nº de citas: 59

    [doi:10.1158/1078-0432.CCR-13-0978]

  • Bosier B, Bellocchio L, Metna-Laurent M, Soria-Gomez E, Matias I, Hebert-Chatelain E, Cannich A, Maitre M, Leste-Lasserre T, Cardinal P, Mendizabal-Zubiaga J, Canduela MJ, Reguero L, Hermans E, Grandes P, Cota D, Marsicano G.

    Astroglial CB1 cannabinoid receptors regulate leptin signaling in mouse brain astrocytes

    Molecular metabolism . 2(4): 393-404. Nº de citas: 57

    [doi:10.1016/j.molmet.2013.08.001]

  • Ostapchenko VG, Beraldo FH, Guimarães AL, Mishra S, Guzman M, Fan J, Martins VR, Prado VF, Prado MA.

    Increased prion protein processing and expression of metabotropic glutamate receptor 1 in a mouse model of Alzheimer's disease

    JOURNAL OF NEUROCHEMISTRY . 127(3): 415-425. Nº de citas: 32

    [doi:10.1111/jnc.12296]

  • Galve-Roperh I, Chiurchiù V, Díaz-Alonso J, Bari M, Guzmán M, Maccarrone M.

    Cannabinoid receptor signaling in progenitor/stem cell proliferation and differentiation

    PROGRESS IN LIPID RESEARCH . 52(4): 633-650. Nº de citas: 174

    [doi:10.1016/j.plipres.2013.05.004]

  • Salazar M, Lorente M, García-Taboada E, Hernández-Tiedra S, Davila D, Francis SE, Guzmán M, Kiss-Toth E, Velasco G.

    The pseudokinase tribbles homologue-3 plays a crucial role in cannabinoid anticancer action

    BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS . 1831(10, SI): 1573-1578. Nº de citas: 41

    [doi:10.1016/j.bbalip.2013.03.014]

  • Bishay P, Häussler A, Lim HY, Oertel B, Galve-Roperh I, Ferreirós N, Tegeder I.

    Anandamide deficiency and heightened neuropathic pain in aged mice

    Neuropharmacology . 71: 204-215. Nº de citas: 20

    [doi:10.1016/j.neuropharm.2013.03.021]

  • Campos AC, Ortega Z, Palazuelos J, Fogaça MV, Aguiar DC, Díaz-Alonso J, Ortega-Gutiérrez S, Vázquez-Villa H, Moreira FA, Guzmán M, Galve-Roperh I, Guimarães FS.

    The anxiolytic effect of cannabidiol on chronically stressed mice depends on hippocampal neurogenesis: involvement of the endocannabinoid system

    INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY . 16(6): 1407-1419. Nº de citas: 155

    [doi:10.1017/S1461145712001502]

  • Pérez-Gómez E, Andradas C, Flores JM, Quintanilla M, Paramio JM, Guzmán M, Sánchez C.

    The orphan receptor GPR55 drives skin carcinogenesis and is upregulated in human squamous cell carcinomas

    Oncogene . 32(20): 2534-2542. Nº de citas: 60

    [doi:10.1038/onc.2012.278]

  • Fogaça MV, Galve-Roperh I, Guimarães FS, Campos AC.

    Cannabinoids, Neurogenesis and Antidepressant Drugs: Is there a Link?

    CURRENT NEUROPHARMACOLOGY . 11(3): 263-275. Nº de citas: 14

    [doi:10.2174/1570159X11311030003]

  • Bellocchio L, Soria-Gómez E, Quarta C, Metna-Laurent M, Cardinal P, Binder E, Cannich A, Delamarre A, Häring M, Martín-Fontecha M, Vega D, Leste-Lasserre T, Bartsch D, Monory K, Lutz B, Chaouloff F, Pagotto U, Guzman M, Cota D, Marsicano G.

    Activation of the sympathetic nervous system mediates hypophagic and anxiety-like effects of CB1 receptor blockade

    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA . 110(12): 4786-4791. Nº de citas: 76

    [doi:10.1073/pnas.1218573110]

  • Hernán Pérez de la Ossa D, Lorente M, Gil-Alegre ME, Torres S, García-Taboada E, Aberturas Mdel R, Molpeceres J, Velasco G, Torres-Suárez AI.

    Local Delivery of Cannabinoid-Loaded Microparticles Inhibits Tumor Growth in a Murine Xenograft Model of Glioblastoma Multiforme

    Plos One . 8(1): . Nº de citas: 56

    [doi:10.1371/journal.pone.0054795]

  • Casarejos MJ, Perucho J, Gomez A, Muñoz MP, Fernandez-Estevez M, Sagredo O, Fernandez Ruiz J, Guzman M, de Yebenes JG, Mena MA.

    Natural Cannabinoids Improve Dopamine Neurotransmission and Tau and Amyloid Pathology in a Mouse Model of Tauopathy

    JOURNAL OF ALZHEIMERS DISEASE . 35(3): 525-539. Nº de citas: 64

    [doi:10.3233/JAD-130050]

  • Pamplona FA, Ferreira J, Menezes de Lima O, Duarte FS, Bento AF, Forner S, Villarinho JG, Bellocchio L, Bellochio L, Wotjak CT, Lerner R, Monory K, Lutz B, Canetti C, Matias I, Calixto JB, Marsicano G, Guimarães MZ, Takahashi RN.

    Anti-inflammatory lipoxin A(4) is an endogenous allosteric enhancer of CB1 cannabinoid receptor

    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA . 109(51): 21134-21139. Nº de citas: 128

    [doi:10.1073/pnas.1202906109]

  • Díaz-Alonso J, Guzmán M, Galve-Roperh I.

    Endocannabinoids via CB1 receptors act as neurogenic niche cues during cortical development

    PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES . 367(1607, SI): 3229-3241. Nº de citas: 56

    [doi:10.1098/rstb.2011.0385]

  • Díaz-Alonso J, Aguado T, Wu CS, Palazuelos J, Hofmann C, Garcez P, Guillemot F, Lu HC, Lutz B, Guzmán M, Galve-Roperh I.

    The CB1 Cannabinoid Receptor Drives Corticospinal Motor Neuron Differentiation through the Ctip2/Satb2 Transcriptional Regulation Axis

    JOURNAL OF NEUROSCIENCE . 32(47): 16651-16665. Nº de citas: 58

    [doi:10.1523/JNEUROSCI.0681-12.2012]

  • Caffarel MM, Andradas C, Pérez-Gómez E, Guzmán M, Sánchez C.

    Cannabinoids: A new hope for breast cancer therapy?

    CANCER TREATMENT REVIEWS . 38(7): 911-918. Nº de citas: 69

    [doi:10.1016/j.ctrv.2012.06.005]

  • Cardinal P, Bellocchio L, Clark S, Cannich A, Klugmann M, Lutz B, Marsicano G, Cota D.

    Hypothalamic CB1 Cannabinoid Receptors Regulate Energy Balance in Mice

    Endocrinology . 153(9): 4136-4143. Nº de citas: 84

    [doi:10.1210/en.2012-1405]

  • Velasco G, Sánchez C, Guzmán M.

    Towards the use of cannabinoids as antitumour agents

    NATURE REVIEWS CANCER . 12(6): 436-444. Nº de citas: 228

    [doi:10.1038/nrc3247]