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Enfermedades neurodegenerativas: mecanismos patogénicos

Buscador de publicaciones

Sólo se han incluido artículos originales, editoriales y revisiones.

  • Huerga-Gomez, Alba, Aguado, Tania, Sanchez-de la Torre, Anibal, Bernal-Chico, Ana, Matute, Carlos, Mato, Susana, Guzman, Manuel, Galve-Roperh, Ismael, Palazuelos, Javier.

    Delta(9)-Tetrahydrocannabinol promotes oligodendrocyte development and CNS myelination in vivo

    Glia . 69(3): 532-545. Nº de citas: 15

    [doi:10.1002/glia.23911]

  • Paraiso-Luna, Juan, Aguareles, Jose, Martin, Ricardo, Ayo-Martin, Ane C, Simon-Sanchez, Samuel, Garcia-Rincon, Daniel, Costas-Insua, Carlos, Garcia-Taboada, Elena, de Salas-Quiroga, Adan, Diaz-Alonso, Javier, Liste, Isabel, Sanchez-Prieto, Jose, Cappello, Silvia, Guzman, Manuel, Galve-Roperh, Ismael.

    Endocannabinoid signalling in stem cells and cerebral organoids drives differentiation to deep layer projection neurons via CB1 receptors.

    DEVELOPMENT . 147(24): . Nº de citas: 6

    [doi:10.1242/dev.192161]

  • Blazquez, Cristina, Ruiz-Calvo, Andrea, Bajo-Graneras, Raquel, Baufreton, Jerome M., Resel, Eva, Varilh, Marjorie, Pagano Zottola, Antonio C., Mariani, Yamuna, Cannich, Astrid, Rodriguez-Navarro, Jose A., Marsicano, Giovanni, Galve-Roperh, Ismael, Bellocchio, Luigi, Guzman, Manuel.

    Cannabinoid-induced motor dysfunctionviaautophagy inhibition

    Autophagy . 16(12): 2289-2291. Nº de citas: 1

    [doi:10.1080/15548627.2020.1827560]

  • Bartoll, Adrian, Toledano-Zaragoza, Ana, Casas, Josefina, Guzman, Manuel, Schuchman, Edward H., Ledesma, Maria Dolores.

    Inhibition of fatty acid amide hydrolase prevents pathology in neurovisceral acid sphingomyelinase deficiency by rescuing defective endocannabinoid signaling

    EMBO MOLECULAR MEDICINE . 12(11): . Nº de citas: 11

    [doi:10.15252/emmm.201911776]

  • Blazquez, Cristina, Ruiz-Calvo, Andrea, Bajo-Graneras, Raquel, Baufreton, Jerome M., Resel, Eva, Varilh, Marjorie, Pagano Zottola AC, Mariani, Yamuna, Cannich, Astrid, Rodriguez-Navarro, Jose A., Marsicano, Giovanni, Galve-Roperh, Ismael, Bellocchio, Luigi, Guzman, Manuel.

    Inhibition of striatonigral autophagy as a link between cannabinoid intoxication and impairment of motor coordination

    ELIFE . 9: . Nº de citas: 5

    [doi:10.7554/eLife.56811]

  • Jimenez-Blasco, Daniel, Busquets-Garcia, Arnau, Hebert-Chatelain, Etienne, Serrat, Roman, Vicente-Gutierrez, Carlos, Ioannidou, Christina, Gomez-Sotres, Paula, Lopez-Fabuel, Irene, Resch-Beusher, Monica, Resel, Eva, Arnouil, Dorian, Saraswat, Dave, Varilh, Marjorie, Cannich, Astrid, Julio-Kalajzic, Francisca, Bonilla-Del Rio, Itziar, Almeida, Angeles, Puente, Nagore, Achicallende, Svein, Lopez-Rodriguez, Maria-Luz, Jolle, Charlotte, Deglon, Nicole, Pellerin, Luc, Josephine, Charlene, Bonvento, Gilles, Panatier, Aude, Lutz, Beat, Piazza, Pier-Vincenzo, Guzman, Manuel, Bellocchio, Luigi, Bouzier-Sore, Anne-Karine, Grandes, Pedro, Bolaños JP, Marsicano, Giovanni.

    Glucose metabolism links astroglial mitochondria to cannabinoid effects

    Nature . 583(7817): 603-608. Nº de citas: 126

    [doi:10.1038/s41586-020-2470-y]

  • Fernandez-Ruiz, Javier, Galve-Roperh, Ismael, Sagredo, Onintza, Guzman, Manuel.

    Possible therapeutic applications of cannabis in the neuropsychopharmacology field

    EUROPEAN NEUROPSYCHOPHARMACOLOGY . 36: 217-234. Nº de citas: 19

    [doi:10.1016/j.euroneuro.2020.01.013]

  • Moreno-Delgado D, Puigdellívol M, Moreno E, Rodríguez-Ruiz M, Botta J, Gasperini P, Chiarlone A, Howell LA, Scarselli M, Casadó V, Cortés A, Ferré S, Guzmán M, Lluís C, Alberch J, Canela EI, Ginés S, McCormick PJ.

    Modulation of dopamine D 1 receptors via histamine H 3 receptors is a novel therapeutic target for Huntington's disease.

    ELIFE . 9: . Nº de citas: 16

    [doi:10.7554/eLife.51093]

  • Navas-Olive, Andrea, Valero, Manuel, Jurado-Parras, Teresa, de Salas-Quiroga, Adan, Averkin, Robert G., Gambino, Giuditta, Cid, Elena, de la Prida, Liset M..

    Multimodal determinants of phase-locked dynamics across deep-superficial hippocampal sublayers during theta oscillations

    NATURE COMMUNICATIONS . 11(1): 2217-2217. Nº de citas: 31

    [doi:10.1038/s41467-020-15840-6]

  • de Salas-Quiroga, Adan, Garcia-Rincon, Daniel, Gomez-Dominguez, Daniel, Valero, Manuel, Simon-Sanchez, Samuel, Paraiso-Luna, Juan, Aguareles, Jose, Pujadas, Mitona, Muguruza, Carolina, Callado, Luis F., Lutz, Beat, Guzman, Manuel, de la Prida LM, Galve-Roperh, Ismael.

    Long-term hippocampal interneuronopathy drives sex-dimorphic spatial memory impairment induced by prenatal THC exposure

    NEUROPSYCHOPHARMACOLOGY . 45(5): 877-886. Nº de citas: 36

    [doi:10.1038/s41386-020-0621-3]

  • Abrams, Donald I., Guzman, Manuel.

    Can Cannabis Cure Cancer?

    JAMA Oncology . 6(3): 323-324. Nº de citas: 9

    [doi:10.1001/jamaoncol.2019.5983]

  • Ruiz-Calvo A, Bajo-Grañeras R, Maroto IB, Zian D, Grabner GF, García-Taboada E, Resel E, Zechner R, Zimmermann R, Ortega-Gutiérrez S, Galve-Roperh I, Bellocchio L, Guzmán M.

    Astroglial monoacylglycerol lipase controls mutant huntingtin-induced damage of striatal neurons.

    Neuropharmacology . 150: 134-144. Nº de citas: 11

    [doi:10.1016/j.neuropharm.2019.03.027]

  • Aguareles J, Paraíso-Luna J, Palomares B, Bajo-Grañeras R, Navarrete C, Ruiz-Calvo A, García-Rincón D, García-Taboada E, Guzmán M, Muñoz E, Galve-Roperh I.

    Oral administration of the cannabigerol derivative VCE-003.2 promotes subventricular zone neurogenesis and protects against mutant huntingtin-induced neurodegeneration.

    Translational Neurodegeneration . 8: 9-9. Nº de citas: 17

    [doi:10.1186/s40035-019-0148-x]

  • Blasco-Benito S, Moreno E, Seijo-Vila M, Tundidor I, Andradas C, Caffarel MM, Caro-Villalobos M, Urigüen L, Diez-Alarcia R, Moreno-Bueno G, Hernández L, Manso L, Homar-Ruano P, McCormick PJ, Bibic L, Bernadó-Morales C, Arribas J, Canals M, Casadó V, Canela EI, Guzmán M, Pérez-Gómez E, Sánchez C.

    Therapeutic targeting of HER2-CB 2 R heteromers in HER2-positive breast cancer.

    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA . 116(9): 3863-3872. Nº de citas: 30

    [doi:10.1073/pnas.1815034116]

  • García-Rincón D, Díaz-Alonso J, Paraíso-Luna J, Ortega Z, Aguareles J, de Salas-Quiroga A, Jou C, de Prada I, Martínez-Cerdeño V, Aronica E, Guzmán M, Pérez-Jiménez MÁ, Galve-Roperh I.

    Contribution of Altered Endocannabinoid System to Overactive mTORC1 Signaling in Focal Cortical Dysplasia.

    FRONTIERS IN PHARMACOLOGY . 9: 1508-1508. Nº de citas: 6

    [doi:10.3389/fphar.2018.01508]

  • Roig-Puiggros S, Vigouroux RJ, Beckman D, Bocai NI, Chiou B, Davimes J, Gomez G, Grassi S, Hoque A, Karikari TK, Kiffer F, Lopez M, Lunghi G, Mazengenya P, Meier S, Olguín-Albuerne M, Oliveira MM, Paraíso-Luna J, Pradhan J, Radiske A, Ramos-Hryb AB, Ribeiro MC, Schellino R, Selles MC, Singh S, Theotokis P, Chédotal A.

    Construction and reconstruction of brain circuits: normal and pathological axon guidance.

    JOURNAL OF NEUROCHEMISTRY . 153(1): 10-32. Nº de citas: 10

    [doi:10.1111/jnc.14900]

  • Sagredo O, Palazuelos J, Gutierrez-Rodriguez A, Satta V, Galve-Roperh I, Martínez-Orgado J.

    Cannabinoid signalling in the immature brain: Encephalopathies and neurodevelopmental disorders.

    BIOCHEMICAL PHARMACOLOGY . 157: 85-96. Nº de citas: 9

    [doi:10.1016/j.bcp.2018.08.014]

  • Blasco-Benito S, Seijo-Vila M, Caro-Villalobos M, Tundidor I, Andradas C, García-Taboada E, Wade J, Smith S, Guzmán M, Pérez-Gómez E, Gordon M, Sánchez C.

    Appraising the entourage effect: Antitumor action of a pure cannabinoid versus a botanical drug preparation in preclinical models of breast cancer.

    BIOCHEMICAL PHARMACOLOGY . 157: 285-293.

    [doi:10.1016/j.bcp.2018.06.025]