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Biomarcadores y Abordaje Personalizado del Cáncer (BioPAC)

Buscador de publicaciones

Sólo se han incluido artículos originales, editoriales y revisiones.

  • Bakirdögen D, Görgülü K, Xin J, Richter L, Alcalá S, Ruiz-Cañas L, Dai C, Frank KJ, Wu N, Diakopoulos KN, Ozturk H, Demircioglu D, Peschke K, Ranjan R, Fusco F, Martinez-Useros J, Fernandez-Aceñero MJ, Chhabra NF, López-Gil JC, Ai J, Ruess DA, Kaya-Aksoy E, Schmidt F, Kohlmann L, Berninger A, Yangin H, Schicktanz F, Steiger K, Demir IE, Schmid RM, Reichert M, Adli M, Lesina M, Sainz B Jr, Algül H.

    c-Rel drives pancreatic cancer metastasis through fibronectin-integrin signaling-induced isolation stress resistance and EMT.

    MOLECULAR CANCER . : .

    [doi:10.1186/s12943-025-02486-5]

  • Liaki V, Barrambana S, Kostopoulou M, Lechuga CG, Zamorano-Dominguez E, Acosta D, Morales-Cacho L, Álvarez R, Sun P, Rosas-Perez B, Barrero R, Jiménez-Parrado S, López-García A, San Roman M, López-Gil JC, Drosten M, Sainz B Jr, Musteanu M, Caleiras E, Dusetti N, Poli V, Sánchez-Bueno F, Guerra C, Barbacid M.

    A targeted combination therapy achieves effective pancreatic cancer regression and prevents tumor resistance.

    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA . 122(49): .

    [doi:10.1073/pnas.2523039122]

  • Salazar J, Arranz MJ, Martin-Broto J, Serra M, Palmerini E, Martínez-García J, Juan-Ribelles A, Andion M, Martinez-Trufero J, Gutiérrez G, Echebarria-Barona A, Vaz-Salgado MA, Regueiro A, Alvarez R, Valverde C, Luna P, Blay P, Sebio A.

    VEGF Signaling Pathway Germline Polymorphisms as Prognostic Pharmacogenetic Biomarkers in Localized High-Grade Osteosarcoma Patients from the GEIS-33 Protocol

    PHARMACEUTICALS . 18(12): .

    [doi:10.3390/ph18121855]

  • Vaz-Salgado MÁ, Del Barco S, Sepúlveda JM, Alonso M, Pineda E, Balana C, Martínez-García M, Gironés R.

    Glasdegib in combination with temozolomide and radiotherapy in adult patients with newly diagnosed glioblastoma: the phase Ib/II GEINO 1602 trial

    NATURE COMMUNICATIONS . 17(1): 86-86.

    [doi:10.1038/s41467-025-66747-z]

  • Urbanova M, Viol F, Ruiz-Cañas L, Koniaris E, Saksis R, Batres-Ramos S, Earl J, Kataki A, Buocikova V, Burikova M, Cihova M, Rojikova L, Makovicky P, Matuskova M, Kohl Y, Riedmayer A, Makova M, Baciak L, Gogola D, Rogoza O, Rovite V, Sainz B Jr, Smolkova B, Schrader J.

    Aurora kinase A inhibition as a synthetic lethality strategy in ARID1A-mutated gastroenteropancreatic neuroendocrine carcinoma

    CANCER LETTERS . 634: 218033-218033.

    [doi:10.1016/j.canlet.2025.218033]

  • Xue N, Sabroso-Lasa S, Merino X, Munzo-Beltran M, Schuurmans M, Olano M, Estudillo L, Ledesma-Carbayo MJ, Liu J, Fan R, Hermans JJ, van Eijck C, Malats N.

    A fusion-based deep-learning algorithm predicts PDAC metastasis based on primary tumour CT images: a multinational study

    Gut . 74(12): 2024-2034.

    [doi:10.1136/gutjnl-2024-334237]

  • Rabadan R, Filip I, Balsells J, López de Maturana E, Langtry A, Alonso L, Sabroso-Lasa S, Moreno-Oya A, Gómez-Rubio P, Molina-Montes E, Márquez M, Milne R, Alfaro A, Lobato T, Estudillo L, Real FX, Malats N, Scarpa A, Lawlor R, Beghelli S, Alvarez-Gallego R, Cubillo A, Hidalgo M, Peinado P, Salas I, Rodríguez Pascual J, Carrato A, Earl J, Caminoa A, Guillén-Ponce C, Rodríguez-Garrote M, Longo-Muñoz F, Ferreiro R, Pachón V, Vaz MÁ, Muñoz M, Iglesias M, Ilzarbe L, Álvarez-Urturi C, Bessa X, Bory F, Márquez L, Poves I, Burdío F, Grande L, Gimeno J, Molero X, Guarner L, Balcells J, Salcedo M, Merino X, Michalski CW, Esposito I, Kleeff J, Kong B, Mota C, Löhr MJ, Huang J, Verbeke C, Ye W, Yu J, Loinaz C, Perea J, Rodríguez-Peralto JL, Teijo A, Peláez P, Farré A, Mora J, Martín M, Artigas V, Guarner C, Sancho FJ, Concepción M, Ramón Y Cajal T, Szafranska J, O'Rorke M, Murray L, Cantwell M, Barberà VM, Gallego J, Tardón A, Barneo L, Rodriguez-Suarez MM, Domínguez-Muñoz E, Pazos Y, Lozano A, Luaces M, Blanco-Antona F, Sayagués Manzano JM, Gutiérrez Troncoso ML, Orfao de Matos A, Muñoz-Bellvís L, Gress TM, Buchholz M, Neesse A, Greenhalf W, Costello E, Crnogorac-Jurcevic T, Kocher HM, Bhattacharya S, Abraham AT, Ennis D, Dowe T, Radon T, O'Driscoll D, Sharp L.

    Deciphering the role of complement system genes in pancreatic cancer susceptibility and prognosis

    NATURE COMMUNICATIONS . 16(1): 10769-10769.

    [doi:10.1038/s41467-025-65811-y]

  • Soler G, Grávalos C, Rivera F, Safont MJ, Virgili AC, Valladares-Ayerbes M, Ferreiro-Monteagudo R, Ortiz-Morales MJ, Polo-Marques E, Kornusova-Bersheva I, Soustre E, Yao W, Élez E.

    Predictive factors of efficacy for FTD/TPI plus bevacizumab in refractory metastatic colorectal cancer patients: a subanalysis of the Spanish cohort from the SUNLIGHT phase III trial.

    CLINICAL & TRANSLATIONAL ONCOLOGY . 27(11): 4203-4213.

    [doi:10.1007/s12094-025-03907-z]

  • Van Laethem JL, Geboes K, Borbath I, Macarulla Mercade T, Lambert A, Cassier P, Prenen H, Mitry E, Blanc JF, Pilla L, Feliu J, Rodriguez Garrote M, Pazo-Cid RA, Gallego I, Smith KE, Nordbladh K, Jimenez DG, Ellmark P, Pico de Coaña Y, Ambarkhane SV, Beatty GL, O'Reilly EM.

    CD40 agonist mitazalimab with mFOLFIRINOX in untreated metastatic pancreatic cancer: Biomarkers associated with outcomes from OPTIMIZE-1

    CELL REPORTS MEDICINE . 6(10): 102407-102407.

    [doi:10.1016/j.xcrm.2025.102407]

  • Palmerini E, Meazza C, Tamburini A, Márquez-Vega C, Bisogno G, Fagioli F, Ferraresi V, Milano GM, Coccoli L, Rubio-San-Simón A, Gallego O, Llinares Riestra ME, Manzitti C, Mora J, Vaz-Salgado MÁ, Luksch R, Mata C, Pierini M, Carretta E, Cesari M, Paioli A, Marrari A, Scotlandi K, Serra M, Asaftei SD, Gambarotti M, Picci P, Ferrari S, Valverde C, Ibrahim T, Broto JM.

    Is There a Role for Mifamurtide in Nonmetastatic High-Grade Osteosarcoma? Results From the Italian Sarcoma Group (ISG/OS-2) and Spanish Sarcoma Group (GEIS-33) Trials

    JOURNAL OF CLINICAL ONCOLOGY . 43(28): 3113-3122. Nº de citas: 2

    [doi:10.1200/JCO-25-00210]

  • Vaz-Salgado MA, Valverde-Morales C, Alvarez R, Asencio JM, Collado E, de Alava E, Diaz Beveridge R, Gómez-Mateo MC, Gracia Alegria I, Marquina G, Martin Broto J, Martínez-Trufero J, Narváez JA, Redondo A, Sebio A, Verges R, Viñals JM, García Del Muro X.

    Diagnosis and Therapy of Soft Tissue Sarcomas: Spanish Group for Research in Sarcomas (GEIS) Guidelines

    Cancers . 17(19): .

    [doi:10.3390/cancers17193158]

  • Abal-Sanisidro M, Palencia-Campos A, Ruiz-Cañas L, García-Fernández J, Cañada-García L, Batres-Ramos S, López-López R, Moreno R, Martín-Pastor M, Sainz B Jr, de la Fuente M.

    Biocompatible self-illuminating sphingomyelin nanosystems for photodynamic-based cancer therapy

    JOURNAL OF CONTROLLED RELEASE . 385: 113982-113982. Nº de citas: 1

    [doi:10.1016/j.jconrel.2025.113982]

  • Avendaño-Ortiz J, Tribaldo A, Ballestero L, Gómez LA, Gracia I, Rodríguez JF, Ramírez NB, Bodoque-Villar R, Vaz-Salgado MÁ, Del Campo R, Redondo-Calvo FJ.

    Antimicrobial Activity of Natural Extracts Against Catheter-Colonizing Methicillin-Resistant Staphylococcus aureus Clinical Isolates

    Biomedicines . 13(9): .

    [doi:10.3390/biomedicines13092150]

  • Parejo-Alonso B, Barneda D, Trabulo SMD, Courtois S, Compte-Sancerni S, Zurkovic J, Ruiz-Cañas L, Zheng Q, Tang J, Gaida MM, Schmitz U, Irun P, Penin-Peyta L, Crusz SM, Jagušt P, Espiau-Romera P, Royo-García A, Gordo-Ortiz A, Yuneva M, Lin ML, Huang S, Yang MH, Lanas A, Sainz B Jr, Thiele C, Heeschen C, Sancho P.

    PPARd Orchestrates a Prometastatic Metabolic Response to Microenvironmental Cues in Pancreatic Cancer

    CANCER RESEARCH . 85(17): 3275-3291. Nº de citas: 1

    [doi:10.1158/0008-5472.CAN-24-3475]

  • Panaitescu-Damian A, Gürcinar I, Stoica V, Paiella S, Hollenbach M, Regel I, Swibold D, Capurso G, Carrato A, Michl P, Arnes L.

    Addressing Pancreatic Exocrine Insufficiency and the Impact of Pancreatic Enzyme Replacement Therapy Shortages in Europe

    UNITED EUROPEAN GASTROENTEROLOGY JOURNAL . : .

    [doi:10.1002/ueg2.70113]

  • Martelli V, Vidal J, Gibert J, Fernández-Rodríguez MC, Linares J, García-Alfonso P, Páez D, Alonso V, Gomez-España MA, Guix M, Santos C, Duran G, Élez E, Garcia-Carbonero R, Ferreiro R, Pineda E, Sastre J, Cano MT, Manzano JL, Losa F, Aranda E, Rivera F, Sibilio A, Toledo R, Tabernero J, Salazar R, Bellosillo B, Montagut C.

    Clinical validation of liquid biopsy-RECIST (LB-RECIST) in metastatic colorectal cancer (mCRC) patients: findings from the PLATFORM-B study

    ESMO open . 10(9): 105760-105760. Nº de citas: 2

    [doi:10.1016/j.esmoop.2025.105760]

  • Melones-Herrero J, Aguilar-Rico F, Matesanz AI, Calés C, Sánchez-Pérez I, Quiroga AG.

    Antiproliferative activity in breast cancer cells of PtL2: A steroid-thiosemicarbazone platinum(II) complex

    JOURNAL OF INORGANIC BIOCHEMISTRY . 270: 112923-112923. Nº de citas: 3

    [doi:10.1016/j.jinorgbio.2025.112923]

  • Cave DD, Di Domenico A, Fantuz M, Ciotola M, Mangini M, Buonaiuto S, Corrado B, Corona M, Saracino F, Andolfi G, Di Biase I, Cucciardi A, Carrer A, Sainz B Jr, Pirozzi T, Re DL, Colonna V, Minchiotti G, De Luca AC, Lonardo E.

    TGF-ß1-mediated downregulation of L1CAM in pancreatic ductal adenocarcinoma drives upregulation of collagen 17A1 and MMP2, facilitating tumor invasiveness and metastasis

    CELL DEATH & DISEASE . 16(1): 592-592.

    [doi:10.1038/s41419-025-07859-8]