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Enfermedades neurodegenerativas: desarrollo de terapias

Buscador de publicaciones

Sólo se han incluido artículos originales, editoriales y revisiones.

  • Satta, Valentina, Alonso, Cristina, Diez, Paula, Martin-Suarez, Soraya, Rubio, Marta, Encinas, Juan M., Fernandez-Ruiz, Javier, Sagredo, Onintza.

    Neuropathological Characterization of a Dravet Syndrome Knock-In Mouse Model Useful for Investigating Cannabinoid Treatments

    FRONTIERS IN MOLECULAR NEUROSCIENCE . 13: 602801-602801. Nº de citas: 12

    [doi:10.3389/fnmol.2020.602801]

  • Burgaz, Sonia, Garcia, Concepcion, Gomez-Canas, Maria, Navarrete, Carmen, Garcia-Martin, Adela, Rolland, Alain, del Rio, Carmen, Casarejos, Maria J., Muñoz E, Gonzalo-Consuegra, Claudia, Muñoz E, Fernandez-Ruiz, Javier.

    Neuroprotection with the cannabigerol quinone derivative VCE-003.2 and its analogs CBGA-Q and CBGA-Q-Salt in Parkinson's disease using 6-hydroxydopamine-lesioned mice

    MOLECULAR AND CELLULAR NEUROSCIENCE . 110: 103583-103583. Nº de citas: 11

    [doi:10.1016/j.mcn.2020.103583]

  • Morales, Paula, Navarro, Gemma, Gomez-Autet, Marc, Redondo, Laura, Fernandez-Ruiz, Javier, Perez-Benito, Laura, Cordomi, Arnau, Pardo, Leonardo, Franco, Rafael, Jagerovic, Nadine.

    Discovery of Homobivalent Bitopic Ligands of the Cannabinoid CB2 Receptor**

    CHEMISTRY-A EUROPEAN JOURNAL . 26(68): 15839-15842. Nº de citas: 15

    [doi:10.1002/chem.202003389]

  • Palomares, Belen, Garrido-Rodriguez, Martin, Gonzalo-Consuegra, Claudia, Gomez-Canas, Maria, Saen-oon, Suwipa, Soliva, Robert, Collado, Juan A., Fernandez-Ruiz, Javier, Morello, Gaetano, Calzado, Marco A., Appendino, Giovanni, Muñoz E.

    Delta(9)-Tetrahydrocannabinolic acid alleviates collagen-induced arthritis: Role of PPAR gamma and CB(1)receptors

    BRITISH JOURNAL OF PHARMACOLOGY . 177(17): 4034-4054. Nº de citas: 9

    [doi:10.1111/bph.15155]

  • Espadas, Isabel, Keifman, Ettel, Palomo-Garo, Cristina, Burgaz, Sonia, Garcia, Concepcion, Fernandez-Ruiz, Javier, Moratalla, Rosario.

    Beneficial effects of the phytocannabinoid Delta(9)-THCV in L-DOPA-induced dyskinesia in Parkinson's disease

    NEUROBIOLOGY OF DISEASE . 141: 104892-104892. Nº de citas: 15

    [doi:10.1016/j.nbd.2020.104892]

  • Fernandez-Ruiz, Javier, Galve-Roperh, Ismael, Sagredo, Onintza, Guzman, Manuel.

    Possible therapeutic applications of cannabis in the neuropsychopharmacology field

    EUROPEAN NEUROPSYCHOPHARMACOLOGY . 36: 217-234. Nº de citas: 19

    [doi:10.1016/j.euroneuro.2020.01.013]

  • Martinez-Gonzalez, Loreto, Rodriguez-Cueto, Carmen, Cabezudo, Diego, Bartolome, Fernando, Andres-Benito, Pol, Ferrer, Isidro, Gil, Carmen, Martin-Requero, Angeles, Fernandez-Ruiz, Javier, Martinez, Ana, de Lago, Eva.

    Motor neuron preservation and decrease of in vivo TDP-43 phosphorylation by protein CK-1 delta kinase inhibitor treatment

    SCIENTIFIC REPORTS . 10(1): 4449-4449. Nº de citas: 35

    [doi:10.1038/s41598-020-61265-y]

  • Fernandez-Trapero, Maria, Perez-Diaz, Carmen, Espejo-Porras, Francisco, de Lago, Eva, Fernandez-Ruiz, Javier.

    Pharmacokinetics of Sativex (R) in Dogs: Towards a Potential Cannabinoid-Based Therapy for Canine Disorders

    Biomolecules . 10(2): . Nº de citas: 17

    [doi:10.3390/biom10020279]

  • Götz MR, Collado JA, Fernández-Ruiz J, Fiebich BL, García-Toscano L, Gómez-Cañas M, Koch O, Leha A, Muñoz E, Navarrete C, Pazos MR, Holzgrabe U.

    Structure-Effect Relationships of Novel Semi-Synthetic Cannabinoid Derivatives.

    FRONTIERS IN PHARMACOLOGY . 10: 1284-1284. Nº de citas: 5

    [doi:10.3389/fphar.2019.01284]

  • Ceprián M, Vargas C, García-Toscano L, Penna F, Jiménez-Sánchez L, Achicallende S, Elezgarai I, Grandes P, Hind W, Pazos MR, Martínez-Orgado J.

    Cannabidiol Administration Prevents Hypoxia-Ischemia-Induced Hypomyelination in Newborn Rats.

    FRONTIERS IN PHARMACOLOGY . 10: 1131-1131. Nº de citas: 16

    [doi:10.3389/fphar.2019.01131]

  • Burgaz S, García C, Gómez-Cañas M, Muñoz E, Fernández-Ruiz J.

    Development of An Oral Treatment with the PPAR-?-Acting Cannabinoid VCE-003.2 Against the Inflammation-Driven Neuronal Deterioration in Experimental Parkinson's Disease.

    Molecules . 24(15): . Nº de citas: 17

    [doi:10.3390/molecules24152702]

  • Ucha M, Coria SM, Núñez AE, Santos-Toscano R, Roura-Martínez D, Fernández-Ruiz J, Higuera-Matas A, Ambrosio E.

    Morphine self-administration alters the expression of translational machinery genes in the amygdala of male Lewis rats.

    JOURNAL OF PSYCHOPHARMACOLOGY . 33(7): 882-893. Nº de citas: 6

    [doi:10.1177/0269881119836206]

  • Fernández-Ruiz J.

    The biomedical challenge of neurodegenerative disorders: an opportunity for cannabinoid-based therapies to improve on the poor current therapeutic outcomes.

    BRITISH JOURNAL OF PHARMACOLOGY . 176(10): 1370-1383. Nº de citas: 31

    [doi:10.1111/bph.14382]

  • Espejo-Porras F, García-Toscano L, Rodríguez-Cueto C, Santos-García I, de Lago E, Fernández-Ruiz J.

    Targeting glial cannabinoid CB 2 receptors to delay the progression of the pathological phenotype in TDP-43 (A315T) transgenic mice, a model of amyotrophic lateral sclerosis.

    BRITISH JOURNAL OF PHARMACOLOGY . 176(10): 1585-1600. Nº de citas: 30

    [doi:10.1111/bph.14216]

  • Gómez-Ruiz M, Rodríguez-Cueto C, Luna-Piñel E, Hernández-Gálvez M, Fernández-Ruiz J.

    Endocannabinoid System in Spinocerebellar Ataxia Type-3 and Other Autosomal-Dominant Cerebellar Ataxias: Potential Role in Pathogenesis and Expected Relevance as Neuroprotective Targets.

    FRONTIERS IN MOLECULAR NEUROSCIENCE . 12: 94-94. Nº de citas: 8

    [doi:10.3389/fnmol.2019.00094]

  • Sagredo O, Palazuelos J, Gutierrez-Rodriguez A, Satta V, Galve-Roperh I, Martínez-Orgado J.

    Cannabinoid signalling in the immature brain: Encephalopathies and neurodevelopmental disorders.

    BIOCHEMICAL PHARMACOLOGY . 157: 85-96. Nº de citas: 9

    [doi:10.1016/j.bcp.2018.08.014]

  • Aymerich MS, Aso E, Abellanas MA, Tolon RM, Ramos JA, Ferrer I, Romero J, Fernández-Ruiz J.

    Cannabinoid pharmacology/therapeutics in chronic degenerative disorders affecting the central nervous system.

    BIOCHEMICAL PHARMACOLOGY . 157: 67-84. Nº de citas: 51

    [doi:10.1016/j.bcp.2018.08.016]

  • Rodríguez-Cueto C, Santos-García I, García-Toscano L, Espejo-Porras F, Bellido M, Fernández-Ruiz J, Muñoz E, de Lago E.

    Neuroprotective effects of the cannabigerol quinone derivative VCE-003.2 in SOD1 G93A transgenic mice, an experimental model of amyotrophic lateral sclerosis.

    BIOCHEMICAL PHARMACOLOGY . 157: 217-226. Nº de citas: 33

    [doi:10.1016/j.bcp.2018.07.049]